Bioanalytical technique for determination of tasimelteon in human plasma by LC-MS/MS and its application to pharmacokinetic study in humans.

Adult Benzofurans / blood Chromatography, Liquid / methods Cyclopropanes / blood Humans Limit of Detection Linear Models Liquid-Liquid Extraction Male Reproducibility of Results Tandem Mass Spectrometry / methods Young Adult
human plasma liquid chromatography-tandem mass spectrometry liquid-liquid extraction method validation tasimelteon

Journal

Biomedical chromatography : BMC
ISSN: 1099-0801
Titre abrégé: Biomed Chromatogr
Pays: England
ID NLM: 8610241

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 25 08 2018
revised: 25 10 2018
accepted: 31 10 2018
pubmed: 10 11 2018
medline: 5 3 2019
entrez: 10 11 2018
Statut: ppublish

Résumé

A highly sensitive, specific and rapid liquid chromatography-tandem mass spectrometry technique for the quantification of tasimelteon in human plasma has been developed and validated using tasimelteon-d

Identifiants

DOI: 10.1002/bmc.4431 PMID: 30412929
pubmed: 30412929
doi: 10.1002/bmc.4431
doi:

Substances chimiques

Benzofurans 0
Cyclopropanes 0
tasimelteon SHS4PU80D9

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e4431

Informations de copyright

© 2018 John Wiley & Sons, Ltd.

Auteurs

Siva Sankara Rao Yadlapalli (SSR)

Department of Chemistry, GITAM University, Hyderabad, India.

Vijaya Kumari Karra (VK)

Wellquest Clinical Research Laboratories, Ramanthapur, Hyderabad, India.

Vinutha Kommineni (V)

Sri Venkateswara College of Pharmacy, Madhapur, Hyderabad, India.

Naresh Kumar Katari (NK)

Department of Chemistry, GITAM University, Hyderabad, India.

Surendra Babu Manabolu Surya (SB)

Department of Chemistry, GITAM University, Hyderabad, India.
ORCID: 0000-0001-9938-1242

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Bioanalytical technique for determination of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzofuranes › Bioanalytical technique for determination of...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Chromatographie › Chromatographie en phase liquide › Bioanalytical technique for determination of...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures alicycliques › Cyclopropanes › Bioanalytical technique for determination of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Bioanalytical technique for determination of...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Sensibilité et spécificité › Limite de détection › Bioanalytical technique for determination of...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Analyse de régression › Modèles linéaires › Bioanalytical technique for determination of...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Fractionnement chimique › Extraction liquide-liquide › Bioanalytical technique for determination of...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Méthodologie en recherche épidémiologique › Reproductibilité des résultats › Bioanalytical technique for determination of...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Spectrométrie de masse en tandem › Bioanalytical technique for determination of...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Jeune adulte › Bioanalytical technique for determination of...