Specimen Pooling as a Diagnostic Strategy for Microbiologic Confirmation in Children with Intrathoracic Tuberculosis.

Child Child, Preschool Colony Count, Microbial Female Humans Infant Male Mycobacterium tuberculosis / isolation & purification Prospective Studies Sensitivity and Specificity Specimen Handling / methods Sputum / microbiology Thorax / microbiology Tuberculosis, Pulmonary / diagnosis

Journal

The Pediatric infectious disease journal
ISSN: 1532-0987
Titre abrégé: Pediatr Infect Dis J
Pays: United States
ID NLM: 8701858

Informations de publication

Date de publication:
06 2019
Historique:
pubmed: 13 11 2018
medline: 1 5 2020
entrez: 13 11 2018
Statut: ppublish

Résumé

Three-hundred four young children with suspected pulmonary tuberculosis had a gastric aspirate, induced sputum and nasopharyngeal aspirate collected on each of 2 consecutive weekdays. Specimens collected on the second day were pooled in the laboratory for each child individually. The diagnostic yield by Xpert and culture from pooled specimens was not significantly different to a single gastric aspirate.

Identifiants

DOI: 10.1097/INF.0000000000002240 PMID: 30418355 PMC: PMC6509014
pubmed: 30418355
doi: 10.1097/INF.0000000000002240
pmc: PMC6509014
mid: NIHMS1511389
doi:

Types de publication

Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e128-e131

Subventions

Organisme : NICHD NIH HHS
ID : HHSN275201800001C
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI068632
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI068634
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI068616
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI106716
Pays : United States
Organisme : NICHD NIH HHS
ID : HHSN275201800001I
Pays : United States

Références

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pubmed: 23394756
PLoS One. 2009;4(4):e5140
pubmed: 19357770
Clin Infect Dis. 2015 Oct 15;61Suppl 3:S179-87
pubmed: 26409281
Arch Dis Child. 2009 Mar;94(3):195-201
pubmed: 18829621
Clin Infect Dis. 2012 May;54(10):1388-96
pubmed: 22474220
Clin Infect Dis. 2012 Oct;55(8):1088-95
pubmed: 22752518
Lancet Respir Med. 2015 Jun;3(6):451-61
pubmed: 25812968
Clin Infect Dis. 2016 May 1;62(9):1161-1168
pubmed: 26908804
Pediatr Infect Dis J. 2017 Sep;36(9):837-843
pubmed: 28151842

Auteurs

Elisabetta Walters (E)

From the Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University.

Marieke M van der Zalm (MM)

From the Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University.

Anne-Marie Demers (AM)

From the Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University.

Andrew Whitelaw (A)

Division of Medical Microbiology, Faculty of Medicine and Health Sciences, Stellenbosch University and National Health Laboratory Service, Tygerberg Hospital.

Megan Palmer (M)

From the Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University.

Corné Bosch (C)

From the Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University.

Heather R Draper (HR)

From the Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University.

H Simon Schaaf (HS)

From the Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University.

Pierre Goussard (P)

Division of Paediatric Pulmonology, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University.

Carl J Lombard (CJ)

Division of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University.
Biostatistics Unit, South African Medical Research Council, South Africa.
School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

Robert P Gie (RP)

From the Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University.

Anneke C Hesseling (AC)

From the Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Specimen Pooling as a Diagnostic Strategy for...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Enfant d'âge préscolaire › Specimen Pooling as a Diagnostic Strategy for...
questionsmedicales.fr › Techniques d'investigation › Techniques de laboratoire clinique › Techniques microbiologiques › Numération de colonies microbiennes › Specimen Pooling as a Diagnostic Strategy for...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Specimen Pooling as a Diagnostic Strategy for...
questionsmedicales.fr › Personnes › Tranches d'âge › Nourrisson › Specimen Pooling as a Diagnostic Strategy for...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Bâtonnets à Gram positif › Bâtonnets asporogènes à Gram positif › Bâtonnets asporogènes réguliers à Gram positif › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis › Specimen Pooling as a Diagnostic Strategy for...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Specimen Pooling as a Diagnostic Strategy for...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Sensibilité et spécificité › Specimen Pooling as a Diagnostic Strategy for...
questionsmedicales.fr › Techniques d'investigation › Techniques de laboratoire clinique › Manipulation d'échantillons › Specimen Pooling as a Diagnostic Strategy for...
questionsmedicales.fr › Liquides et sécrétions biologiques › Sécrétions corporelles › Expectoration › Specimen Pooling as a Diagnostic Strategy for...
questionsmedicales.fr › Régions du corps › Tronc › Thorax › Specimen Pooling as a Diagnostic Strategy for...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Tuberculose pulmonaire › Specimen Pooling as a Diagnostic Strategy for...