Systemic and intraocular factors related to retinal thicknesses variations in patients with Parkinson's disease.


Journal

Parkinsonism & related disorders
ISSN: 1873-5126
Titre abrégé: Parkinsonism Relat Disord
Pays: England
ID NLM: 9513583

Informations de publication

Date de publication:
04 2019
Historique:
received: 08 09 2018
accepted: 05 11 2018
pubmed: 14 11 2018
medline: 15 11 2019
entrez: 14 11 2018
Statut: ppublish

Résumé

Parkinson's disease (PD) is characterized by a neurodegenerative process, which has been previously reported to involve some retinal layers, in particular the peripapillary retinal nerve fiber layer (RNFL) and macular ganglion cell complex (mGCC). When measuring pRNFL and mGCC by Optical Coherence Tomography in PD patients, it should not be neglected the role of possible both sistemic and intraocular factors, which have been proven to modify intraretinal thicknesses measurements. Nonetheless, also dopaminergic drugs administration could represent another important confounding factor, given their neuroprotective effect exerted on retina.

Identifiants

pubmed: 30420111
pii: S1353-8020(18)30486-3
doi: 10.1016/j.parkreldis.2018.11.004
pii:
doi:

Types de publication

Letter Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

234-235

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2018. Published by Elsevier Ltd.

Auteurs

Lorenzo Ferro Desideri (L)

Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Italy. Electronic address: lorenzoferrodes@gmail.com.

Fabio Barra (F)

Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Italy; Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi 10, 16132, Genoa, Italy.

Simone Ferrero (S)

Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Italy; Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi 10, 16132, Genoa, Italy.

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Classifications MeSH