Fluorine-19 MRI at 21.1 T: enhanced spin-lattice relaxation of perfluoro-15-crown-5-ether and sensitivity as demonstrated in ex vivo murine neuroinflammation.


Journal

Magma (New York, N.Y.)
ISSN: 1352-8661
Titre abrégé: MAGMA
Pays: Germany
ID NLM: 9310752

Informations de publication

Date de publication:
Feb 2019
Historique:
received: 04 07 2018
accepted: 18 10 2018
revised: 16 10 2018
pubmed: 14 11 2018
medline: 23 7 2019
entrez: 14 11 2018
Statut: ppublish

Résumé

Fluorine MR would benefit greatly from enhancements in signal-to-noise ratio (SNR). This study examines the sensitivity gain of We studied perfluoro-15-crown-5-ether (PFCE) at both field strengths (B Compared to 9.4 T, an SNR gain of > 3 was observed for pure PFCE and > 2 for PFCE NPs at 21.1 T using 2D-FLASH. A dependency of Enhanced SNR and T

Identifiants

pubmed: 30421250
doi: 10.1007/s10334-018-0710-z
pii: 10.1007/s10334-018-0710-z
pmc: PMC6514110
doi:

Substances chimiques

Contrast Media 0
Crown Ethers 0
Spin Labels 0
perfluoro-15-crown-5-ether 0
Fluorine 284SYP0193

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

37-49

Subventions

Organisme : National High Magnetic Field Laboratory (US)
ID : 227000-110

Références

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Auteurs

Sonia Waiczies (S)

Experimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany. sonia.waiczies@mdc-berlin.de.

Jens T Rosenberg (JT)

The National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL, USA.

Andre Kuehne (A)

MRI TOOLS GmbH, Berlin, Germany.

Ludger Starke (L)

Experimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.

Paula Ramos Delgado (PR)

Experimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.

Jason M Millward (JM)

Experimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.

Christian Prinz (C)

Experimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.

Joao Dos Santos Periquito (J)

Experimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.

Andreas Pohlmann (A)

Experimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.

Helmar Waiczies (H)

MRI TOOLS GmbH, Berlin, Germany.

Thoralf Niendorf (T)

Experimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.
MRI TOOLS GmbH, Berlin, Germany.
Experimental and Clinical Research Center, A Joint Cooperation Between the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.

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Classifications MeSH