Increase of global DNA methylation patterns in beauty salon workers exposed to low levels of formaldehyde.

Brazilian blowout Epigenetic Formaldehyde Formic acid Global DNA methylation Hair straightening Occupational exposure

Journal

Environmental science and pollution research international
ISSN: 1614-7499
Titre abrégé: Environ Sci Pollut Res Int
Pays: Germany
ID NLM: 9441769

Informations de publication

Date de publication:
Jan 2019
Historique:
received: 08 05 2018
accepted: 05 11 2018
pubmed: 14 11 2018
medline: 23 2 2019
entrez: 14 11 2018
Statut: ppublish

Résumé

Formaldehyde (FA) is a carcinogenic aldehyde illegally added to creams as a hair straightening agent for the Brazilian blowout (BB). This study aimed to investigate the possible effects of occupational exposure to FA on global DNA methylation in salon workers with different exposure levels. FA exposure was monitored using environmental and biological measurements. The study included 49 salon workers divided by FA levels in the workplace into group A (FA < 0.01 ppm; n = 8), group B (0.03 ppm < FA < 0.06 ppm; n = 15), and group C (0.08 ppm < FA < 0.24 ppm; n = 26). The global DNA methylation levels were 3.12%, 4.55%, and 4.29% for groups A, B, and C, respectively, with statistically higher values for groups B and C compared to group A (p = 0.002). A correlation was found between FA in passive samplers and global DNA methylation (r

Identifiants

pubmed: 30421373
doi: 10.1007/s11356-018-3674-7
pii: 10.1007/s11356-018-3674-7
doi:

Substances chimiques

Air Pollutants, Occupational 0
Formaldehyde 1HG84L3525

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1304-1314

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Auteurs

Eduardo Barbosa (E)

Analytical Toxicology Laboratory, Universidade Feevale, ERS-239, 2755, Novo Hamburgo, RS, 93525-075, Brazil.
Graduate Program on Toxicology and Analytical Toxicology, Universidade Feevale, Novo Hamburgo, RS, Brazil.

Ana Laura Anibaletto Dos Santos (ALA)

Analytical Toxicology Laboratory, Universidade Feevale, ERS-239, 2755, Novo Hamburgo, RS, 93525-075, Brazil.

Giovana Piva Peteffi (GP)

Analytical Toxicology Laboratory, Universidade Feevale, ERS-239, 2755, Novo Hamburgo, RS, 93525-075, Brazil.

Anelise Schneider (A)

Analytical Toxicology Laboratory, Universidade Feevale, ERS-239, 2755, Novo Hamburgo, RS, 93525-075, Brazil.

Diana Müller (D)

Department of Genetics, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
ADHD Outpatient Program, Adult Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.

Diego Rovaris (D)

Department of Genetics, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
ADHD Outpatient Program, Adult Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.

Claiton Henrique Dotto Bau (CHD)

Department of Genetics, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
ADHD Outpatient Program, Adult Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.

Rafael Linden (R)

Analytical Toxicology Laboratory, Universidade Feevale, ERS-239, 2755, Novo Hamburgo, RS, 93525-075, Brazil.
Graduate Program on Toxicology and Analytical Toxicology, Universidade Feevale, Novo Hamburgo, RS, Brazil.

Marina Venzon Antunes (MV)

Analytical Toxicology Laboratory, Universidade Feevale, ERS-239, 2755, Novo Hamburgo, RS, 93525-075, Brazil.
Graduate Program on Toxicology and Analytical Toxicology, Universidade Feevale, Novo Hamburgo, RS, Brazil.

Mariele Feiffer Charão (MF)

Analytical Toxicology Laboratory, Universidade Feevale, ERS-239, 2755, Novo Hamburgo, RS, 93525-075, Brazil. marielecharao@feevale.br.
Graduate Program on Toxicology and Analytical Toxicology, Universidade Feevale, Novo Hamburgo, RS, Brazil. marielecharao@feevale.br.

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Classifications MeSH