Self-poisoning with 60 tablets of Apixaban, a pharmacokinetics case report.


Journal

British journal of clinical pharmacology
ISSN: 1365-2125
Titre abrégé: Br J Clin Pharmacol
Pays: England
ID NLM: 7503323

Informations de publication

Date de publication:
01 2019
Historique:
received: 20 04 2018
revised: 26 09 2018
accepted: 11 10 2018
pubmed: 14 11 2018
medline: 31 12 2019
entrez: 14 11 2018
Statut: ppublish

Résumé

A 67-year-old man was admitted to the emergency department about 5 h after deliberate self-poisoning with 300 mg of Apixaban. The clinical examination did not show any organ dysfunctions or haemorrhagic signs, and the patient's life was not in danger. The first analysis, upon admission, showed a concentration of 2655 μg l

Identifiants

pubmed: 30421528
doi: 10.1111/bcp.13790
pmc: PMC6303243
doi:

Substances chimiques

Factor Xa Inhibitors 0
Pyrazoles 0
Pyridones 0
Tablets 0
apixaban 3Z9Y7UWC1J

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

270-272

Informations de copyright

© 2018 The British Pharmacological Society.

Références

Br J Clin Pharmacol. 2016 Mar;81(3):482-7
pubmed: 26409027
Br J Clin Pharmacol. 2019 Jan;85(1):270-272
pubmed: 30421528
Am J Cardiovasc Drugs. 2014 Apr;14(2):147-54
pubmed: 24277644
Nucleic Acids Res. 2018 Jan 4;46(D1):D1091-D1106
pubmed: 29149325
Thromb Haemost. 2017 Nov;117(11):2209-2211
pubmed: 28981556
Br J Clin Pharmacol. 2013 Nov;76(5):776-86
pubmed: 23451769
Br J Pharmacol. 2017 Dec;174 Suppl 1:S360-S446
pubmed: 29055035
Am J Emerg Med. 2017 May;35(5):801.e5-801.e6
pubmed: 27884586
Clin Toxicol (Phila). 2016 Nov;54(9):871-873
pubmed: 27436437
Drug Metab Dispos. 2013 Apr;41(4):906-15
pubmed: 23386703
Br J Pharmacol. 2017 Dec;174 Suppl 1:S272-S359
pubmed: 29055034

Auteurs

Bénédicte Franck (B)

Department of Pharmacology and Toxicology, CHU Limoges, F-87000, Limoges, France.

Sylvain Dulaurent (S)

Department of Pharmacology and Toxicology, CHU Limoges, F-87000, Limoges, France.

Souleiman El Balkhi (S)

Department of Pharmacology and Toxicology, CHU Limoges, F-87000, Limoges, France.

Caroline Monchaud (C)

Department of Pharmacology and Toxicology, CHU Limoges, F-87000, Limoges, France.

Nicolas Picard (N)

Department of Pharmacology and Toxicology, CHU Limoges, F-87000, Limoges, France.

Sylvain Couderc (S)

Department of Pharmacology and Toxicology, CHU Limoges, F-87000, Limoges, France.

Pierre Marquet (P)

Department of Pharmacology and Toxicology, CHU Limoges, F-87000, Limoges, France.

Franck Saint-Marcoux (F)

Department of Pharmacology and Toxicology, CHU Limoges, F-87000, Limoges, France.

Jean-Baptiste Woillard (JB)

Department of Pharmacology and Toxicology, CHU Limoges, F-87000, Limoges, France.

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Classifications MeSH