Effectiveness of a Total Meal Replacement Program (OPTIFAST Program) on Weight Loss: Results from the OPTIWIN Study.


Journal

Obesity (Silver Spring, Md.)
ISSN: 1930-739X
Titre abrégé: Obesity (Silver Spring)
Pays: United States
ID NLM: 101264860

Informations de publication

Date de publication:
01 2019
Historique:
received: 01 06 2018
revised: 01 08 2018
accepted: 03 08 2018
pubmed: 14 11 2018
medline: 16 1 2020
entrez: 14 11 2018
Statut: ppublish

Résumé

The aim of this study was to test the effectiveness of the OPTIFAST program (OP), a total meal replacement dietary intervention, compared with a food-based (FB) dietary plan for weight loss. Participants with BMI 30 to 55 kg/m A total of 273 participants (83% of randomized; 135 OP, 138 FB) made up the mITT population. Mean age was 47.1 ± 11.2 years; 82% were female and 71% non-Hispanic white. Baseline BMI was 38.8 ± 5.9 kg/m Compared with an FB approach, OP was more effective with greater sustained weight loss.

Identifiants

pubmed: 30421863
doi: 10.1002/oby.22303
pmc: PMC6587830
doi:

Banques de données

ClinicalTrials.gov
['NCT02635698']

Types de publication

Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

22-29

Subventions

Organisme : NIDDK NIH HHS
ID : P30 DK089503
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001420
Pays : United States

Informations de copyright

© 2018 The Obesity Society.

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Auteurs

Jamy D Ard (JD)

Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston Salem, North Carolina, USA.

Kristina H Lewis (KH)

Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston Salem, North Carolina, USA.

Amy Rothberg (A)

Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA.

Anthony Auriemma (A)

AMITA Health, Alexian Brothers Weight Loss Solutions, Elk Grove Village, Illinois, USA.

Sally L Coburn (SL)

Alaska Premier Health, Anchorage, Alaska, USA.

Sarah S Cohen (SS)

EpidStat Institute, Ann Arbor, Michigan, USA.

Judy Loper (J)

The Central Ohio Nutrition Center, Inc., Gahanna, Ohio, USA.

Laura Matarese (L)

Department of Surgery, East Carolina University Brody School of Medicine, Greenville, North Carolina, USA.

Walter J Pories (WJ)

Department of Surgery, East Carolina University Brody School of Medicine, Greenville, North Carolina, USA.

Seletha Periman (S)

Nestlé Health Science, U.S. Clinical Operations, Bridgewater, New Jersey, USA.

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Classifications MeSH