Primary idiopathic CNS non-amyloidogenic light chain deposition disease complicated by treatment-resistant focal seizure disorder.


Journal

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
ISSN: 1532-2653
Titre abrégé: J Clin Neurosci
Pays: Scotland
ID NLM: 9433352

Informations de publication

Date de publication:
Jan 2019
Historique:
received: 18 06 2018
accepted: 27 10 2018
pubmed: 15 11 2018
medline: 13 2 2019
entrez: 15 11 2018
Statut: ppublish

Résumé

Light chain deposition disease (LCDD) is a systemic disorder characterised by the pathologic deposition of immunoglobulin light chains, which is histologically distinguished from amyloidosis by failure to stain with Congo red. Central nervous system (CNS)-restricted LCDD is among the rarest manifestations. We describe a unique case complicated by focal onset epilepsy with impaired awareness for which control with anticonvulsant therapy proved difficult.

Identifiants

pubmed: 30424969
pii: S0967-5868(18)31065-8
doi: 10.1016/j.jocn.2018.10.123
pii:
doi:

Substances chimiques

Immunoglobulin Light Chains 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

313-315

Informations de copyright

Copyright © 2018 Elsevier Ltd. All rights reserved.

Auteurs

Brian T Grainger (BT)

Department of Haematology, Middlemore Hospital, Auckland, New Zealand.

Samar Issa (S)

Department of Haematology, Middlemore Hospital, Auckland, New Zealand. Electronic address: Samar.Issa@middlemore.co.nz.

Neil E Anderson (NE)

Department of Neurology, Auckland City Hospital, Auckland, New Zealand.

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Classifications MeSH