From Bugs to Bioplastics: Total (+)-Dihydrocarvide Biosynthesis by Engineered Escherichia coli.
(+)-dihydrocarvide monomer
Baeyer-Villiger monooxygenases
bioplastics
engineering
synthetic biology
Journal
Chembiochem : a European journal of chemical biology
ISSN: 1439-7633
Titre abrégé: Chembiochem
Pays: Germany
ID NLM: 100937360
Informations de publication
Date de publication:
15 03 2019
15 03 2019
Historique:
received:
09
10
2018
pubmed:
16
11
2018
medline:
31
12
2019
entrez:
16
11
2018
Statut:
ppublish
Résumé
The monoterpenoid lactone derivative (+)-dihydrocarvide ((+)-DHCD) can be polymerised to form shape-memory polymers. Synthetic biology routes from simple, inexpensive carbon sources are an attractive, alternative route over chemical synthesis from (R)-carvone. We have demonstrated a proof-of-principle in vivo approach for the complete biosynthesis of (+)-DHCD from glucose in Escherichia coli (6.6 mg L
Identifiants
pubmed: 30431225
doi: 10.1002/cbic.201800606
pmc: PMC6850611
doi:
Substances chimiques
Lactones
0
Monoterpenes
0
Glucose
IY9XDZ35W2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
785-792Informations de copyright
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
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