Flavonoids: biological activities and therapeutic potential.


Journal

Natural product research
ISSN: 1478-6427
Titre abrégé: Nat Prod Res
Pays: England
ID NLM: 101167924

Informations de publication

Date de publication:
Mar 2020
Historique:
pubmed: 18 11 2018
medline: 18 4 2020
entrez: 18 11 2018
Statut: ppublish

Résumé

Flavonoids have aroused much interest in research, since they present a great diversity of biological activities observed in vitro, such as: antioxidant effect, modulation of the enzymatic activity and inhibition of cellular proliferation, exerting beneficial effects on the organism, as well as the use of its therapeutic potential. With wide distribution in the plant kingdom represent a class of phenolic compounds that differ in their chemical structure and particular characteristics. The objective of this review was to describe the relevant aspects of flavonoids, reporting the different known groups, the probable mechanisms by which they act, their pharmacological properties and to gain a better understanding of the reported beneficial health effects of these substances. This systematic review consisted of research using scientific databases such as Scopus, Science Direct, PubMed, SciVerse and SciELO, without time limitation. Some pharmacological properties of some flavonoids and their health benefits have been confirmed by previous studies.

Identifiants

pubmed: 30445839
doi: 10.1080/14786419.2018.1493588
doi:

Substances chimiques

Antioxidants 0
Flavonoids 0
Phenols 0
Plant Extracts 0

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

692-705

Auteurs

Mércia Marques Jucá (MM)

Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, Brazil.

Francisco Mauricio Sales Cysne Filho (FMS)

Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, Brazil.

Jamily Cunha de Almeida (JC)

University of Fortaleza, Fortaleza, Brazil.

Dara da Silva Mesquita (DDS)

Health Science Center, School of Medicine, University Centre Christus, Fortaleza, Brazil.

Jéssica Rodrigues de Moraes Barriga (JRM)

Health Science Center, School of Medicine, University Centre Christus, Fortaleza, Brazil.

Kátia Cilene Ferreira Dias (KCF)

Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, Brazil.

Talita Matias Barbosa (TM)

Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, Brazil.

Luna Costa Vasconcelos (LC)

Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, Brazil.

Luzia Kalyne Almeida Moreira Leal (LKAM)

Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, Brazil.

José Eduardo Ribeiro (JE)

Health Science Center, School of Medicine, University Centre Christus, Fortaleza, Brazil.

Silvânia Maria Mendes Vasconcelos (SMM)

Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, Brazil.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH