In vivo voltammetric evidence that locus coeruleus activation predominantly releases norepinephrine in the infralimbic cortex: Effect of acute ethanol.
catecholamines
ethanol
locus coeruleus
prefrontal cortex
voltammetry
Journal
Synapse (New York, N.Y.)
ISSN: 1098-2396
Titre abrégé: Synapse
Pays: United States
ID NLM: 8806914
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
received:
18
09
2018
revised:
11
11
2018
accepted:
12
11
2018
pubmed:
18
11
2018
medline:
24
4
2020
entrez:
18
11
2018
Statut:
ppublish
Résumé
Using fast-scan cyclic voltammetry paired with pharmacology, the authors show that infralimbic catecholamine release following locus coeruleus stimulation is noradrenergic, but not dopaminergic, and not affected by acute ethanol. With previous work, these data suggest differential effects of ethanol on prefrontal norepinephrine and dopamine, a region important in addiction-related pathways.
Substances chimiques
Central Nervous System Depressants
0
Ethanol
3K9958V90M
Norepinephrine
X4W3ENH1CV
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e22080Subventions
Organisme : NIAAA NIH HHS
ID : P50 AA026117-01
Pays : United States
Organisme : NIAAA NIH HHS
ID : AA022449
Pays : United States
Organisme : NIAAA NIH HHS
ID : T32AA007565
Pays : United States
Informations de copyright
© 2018 Wiley Periodicals, Inc.