A Case Report of Meningeal Hemangiopericytoma: A 9-Year Journey from the Brain to the Spine.


Journal

World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275

Informations de publication

Date de publication:
Feb 2019
Historique:
received: 09 09 2018
revised: 02 11 2018
accepted: 04 11 2018
pubmed: 18 11 2018
medline: 21 3 2019
entrez: 18 11 2018
Statut: ppublish

Résumé

Hemangiopericytomas (HPCs) are rare and aggressive vascular mesenchymal tumors. Unlike meningiomas, which have a similar radiologic appearance, these tumors have a higher risk of local recurrence after resection, and distant metastasis can reach up to 23%. Metastases to the vertebral bones from an intracranial HPC are very rare, with so far only 9 cases reported in the literature. We present the case of a 46-year-old man who was surgically treated for a presumed left parieto-occipital falx meningioma in 2008. He presented 9 years later with a thoracic vertebral mass that was causing relentless pain. Reexamination of the cranial pathology allowed correction of the diagnosis performed in 2008 to a meningeal HPC, and the spinal lesion was confirmed after surgery to be a metastatic tumor. The literature lacks randomized controlled trials and large studies defining the natural history of HPC to draw clear recommendations for a precise management of the disease. However, en bloc resection followed by radiation therapy seems to provide the optimal treatment for a long disease-free survival.

Sections du résumé

BACKGROUND BACKGROUND
Hemangiopericytomas (HPCs) are rare and aggressive vascular mesenchymal tumors. Unlike meningiomas, which have a similar radiologic appearance, these tumors have a higher risk of local recurrence after resection, and distant metastasis can reach up to 23%. Metastases to the vertebral bones from an intracranial HPC are very rare, with so far only 9 cases reported in the literature.
CASE DESCRIPTION METHODS
We present the case of a 46-year-old man who was surgically treated for a presumed left parieto-occipital falx meningioma in 2008. He presented 9 years later with a thoracic vertebral mass that was causing relentless pain. Reexamination of the cranial pathology allowed correction of the diagnosis performed in 2008 to a meningeal HPC, and the spinal lesion was confirmed after surgery to be a metastatic tumor.
CONCLUSIONS CONCLUSIONS
The literature lacks randomized controlled trials and large studies defining the natural history of HPC to draw clear recommendations for a precise management of the disease. However, en bloc resection followed by radiation therapy seems to provide the optimal treatment for a long disease-free survival.

Identifiants

pubmed: 30447454
pii: S1878-8750(18)32575-0
doi: 10.1016/j.wneu.2018.11.028
pii:
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

459-463

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Ahmad Sweid (A)

Division of Neurosurgery, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Beirut, Lebanon.

Mohammad Hassan A Noureldine (MHA)

Division of Neurosurgery, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Beirut, Lebanon.

Selim Nasser (S)

Department of Pathology, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Beirut, Lebanon.

Mohammad Badra (M)

Division of Orthopedic Spine Surgery, Clemenceau Medical Center, Beirut, Lebanon.

Ibrahim Saikali (I)

Division of Neurosurgery, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Beirut, Lebanon. Electronic address: ibrahim.saikali@lau.edu.lb.

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