Infertility Treatments and Long-Term Neurologic Morbidity of the Offspring.
Adolescent
Adult
Attention Deficit Disorder with Hyperactivity
/ etiology
Autistic Disorder
/ etiology
Cerebral Palsy
/ etiology
Child
Child, Preschool
Cohort Studies
Female
Fertilization in Vitro
/ adverse effects
Headache
/ etiology
Humans
Infant
Infant, Newborn
Male
Maternal Age
Ovulation Induction
/ adverse effects
Proportional Hazards Models
Risk Factors
Sleep Wake Disorders
/ etiology
Journal
American journal of perinatology
ISSN: 1098-8785
Titre abrégé: Am J Perinatol
Pays: United States
ID NLM: 8405212
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
pubmed:
20
11
2018
medline:
25
6
2020
entrez:
20
11
2018
Statut:
ppublish
Résumé
To determine the risk of long-term neurologic morbidity among children (up to 18 years) born following in vitro fertilization (IVF) or ovulation induction (OI) treatments as compared with spontaneously conceived. A population-based cohort analysis was performed, including data from the perinatal computerized database on all singleton infants born at the Soroka University Medical Center (SUMC) between the years 1991 and 2014. This perinatal database was linked and cross-matched with the SUMC computerized dataset of all pediatric hospitalizations. Neurologic morbidity was significantly more common in IVF (3.7%) and OI (4.1%) offspring as compared with those following spontaneous pregnancies (3.1%; IVF offspring appear to be at an increased risk of long-term neurologic morbidity up to 18 years of age.
Identifiants
pubmed: 30452068
doi: 10.1055/s-0038-1675159
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
949-954Informations de copyright
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Déclaration de conflit d'intérêts
None.