Effect of glycerol on reconstructed human oral mucosa.
Palliative care
dry mouth
moisturizer
saliva
xerostomia
Journal
European journal of oral sciences
ISSN: 1600-0722
Titre abrégé: Eur J Oral Sci
Pays: England
ID NLM: 9504563
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
accepted:
11
10
2018
pubmed:
20
11
2018
medline:
6
8
2019
entrez:
20
11
2018
Statut:
ppublish
Résumé
The majority of severely ill patients experience dry mouth. For institutionalized patients, this condition is commonly treated using glycerol as a lubricant. However, because of its possibly desiccating effect, some countries do not advocate the use of glycerol. This study aimed to investigate dose-dependent effects of glycerol on homeostasis and tissue integrity of in vitro-reconstructed normal human buccal mucosa (RNHBM). Primary keratinocytes and fibroblasts were isolated and expanded from biopsies of mucosa from eight healthy volunteers. Ninety-six samples of RNHBM were prepared and exposed for 24 h to 17%, 42.5%, or 85% glycerol, or to distilled H
Substances chimiques
Glycerol
PDC6A3C0OX
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Pagination
19-26Informations de copyright
© 2018 Eur J Oral Sci.