A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions.


Journal

Nature microbiology
ISSN: 2058-5276
Titre abrégé: Nat Microbiol
Pays: England
ID NLM: 101674869

Informations de publication

Date de publication:
01 2019
Historique:
received: 30 09 2017
accepted: 04 10 2018
pubmed: 21 11 2018
medline: 18 6 2019
entrez: 21 11 2018
Statut: ppublish

Résumé

West Nile virus (WNV), a member of the Flavivirus genus, is a leading cause of viral encephalitis in the United States

Identifiants

pubmed: 30455471
doi: 10.1038/s41564-018-0283-7
pii: 10.1038/s41564-018-0283-7
pmc: PMC6435290
mid: NIHMS1508969
doi:

Substances chimiques

Antibodies, Monoclonal 0
Antibodies, Neutralizing 0
Antibodies, Viral 0
Viral Envelope Proteins 0
West Nile Virus Vaccines 0
glycoprotein E, Flavivirus 145420-18-4

Types de publication

Letter Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

71-77

Subventions

Organisme : NCATS NIH HHS
ID : UL1 TR000445
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI073755
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK058404
Pays : United States
Organisme : NIAID NIH HHS
ID : HHSN272201400018C
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI112541
Pays : United States
Organisme : Intramural NIH HHS
ID : ZIA AI000957-14
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA068485
Pays : United States

Références

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Auteurs

Leslie Goo (L)

Viral Pathogenesis Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Chan Zuckerberg Biohub, San Francisco, CA, USA.

Kari Debbink (K)

Viral Pathogenesis Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

Nurgun Kose (N)

Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN, USA.

Gopal Sapparapu (G)

Department of Pediatrics, and the Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN, USA.

Michael P Doyle (MP)

Department of Pathobiology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.

Alex W Wessel (AW)

Departments of Medicine, Molecular Microbiology, Pathology and Immunology, and The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA.

Justin M Richner (JM)

Departments of Medicine, Molecular Microbiology, Pathology and Immunology, and The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA.
Department of Microbiology and Immunology, University of Illinois at Chicago, Chicago, IL, USA.

Katherine E Burgomaster (KE)

Viral Pathogenesis Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

Bridget C Larman (BC)

Viral Pathogenesis Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

Kimberly A Dowd (KA)

Viral Pathogenesis Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

Michael S Diamond (MS)

Departments of Medicine, Molecular Microbiology, Pathology and Immunology, and The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA.

James E Crowe (JE)

Departments of Pediatrics, Pathobiology, Microbiology and Immunology, and the Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN, USA. james.crowe@vanderbilt.edu.

Theodore C Pierson (TC)

Viral Pathogenesis Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. piersontc@niaid.nih.gov.

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Classifications MeSH