Type 2 inositol 1,4,5-trisphosphate receptor inhibits the progression of pulmonary arterial hypertension via calcium signaling and apoptosis.
Animals
Apoptosis
Calcium
/ metabolism
Calcium Signaling
Cells, Cultured
Disease Models, Animal
Disease Progression
Hypertension, Pulmonary
/ metabolism
Immunohistochemistry
In Situ Nick-End Labeling
Inositol 1,4,5-Trisphosphate Receptors
/ metabolism
Male
Mice
Mice, Inbred C57BL
Muscle, Smooth, Vascular
/ metabolism
Pulmonary Artery
/ pathology
Vasoconstriction
Apoptosis
Chronic hypoxia
Pulmonary artery smooth muscle cells
Store-operated calcium entry
Journal
Heart and vessels
ISSN: 1615-2573
Titre abrégé: Heart Vessels
Pays: Japan
ID NLM: 8511258
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
11
09
2018
accepted:
09
11
2018
pubmed:
22
11
2018
medline:
18
5
2019
entrez:
22
11
2018
Statut:
ppublish
Résumé
Pulmonary arterial hypertension (PAH) is a progressive disease associated with vasoconstriction and remodeling. Intracellular Ca
Identifiants
pubmed: 30460575
doi: 10.1007/s00380-018-1304-4
pii: 10.1007/s00380-018-1304-4
doi:
Substances chimiques
Inositol 1,4,5-Trisphosphate Receptors
0
Ip3r2 protein, mouse
0
Calcium
SY7Q814VUP
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
724-734Subventions
Organisme : Japan Society for the Promotion of Science
ID : JP19790740
Organisme : Japan Society for the Promotion of Science
ID : JP19390288
Organisme : Japan Society for the Promotion of Science
ID : JP21791004
Organisme : Japan Society for the Promotion of Science
ID : JP23591583
Organisme : Japan Society for the Promotion of Science
ID : JP26461619
Organisme : Japan Society for the Promotion of Science
ID : JP17K10153
Organisme : Japan Society for the Promotion of Science
ID : JP16H05359
Références
Nat Cell Biol. 2002 Nov;4(11):E263-72
pubmed: 12415286
Cell Death Dis. 2013 May 16;4:e632
pubmed: 23681227
Am J Physiol Lung Cell Mol Physiol. 2018 May 1;314(5):L724-L735
pubmed: 29388468
Physiol Rev. 2016 Oct;96(4):1261-96
pubmed: 27512009
Front Physiol. 2018 Mar 21;9:257
pubmed: 29618985
Dev Biol. 2016 Oct 1;418(1):89-97
pubmed: 27514653
Am J Physiol Heart Circ Physiol. 2012 Apr 15;302(8):H1546-62
pubmed: 22245772
Circulation. 2000 Nov 28;102(22):2781-91
pubmed: 11094047
PLoS One. 2014 Jun 05;9(6):e99205
pubmed: 24901844
PLoS One. 2010 Sep 01;5(9):
pubmed: 20824138
J Clin Invest. 2000 Feb;105(3):261-70
pubmed: 10675351
Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13861-6
pubmed: 15358862
Apoptosis. 2007 May;12(5):951-68
pubmed: 17294082
Science. 2005 Sep 30;309(5744):2232-4
pubmed: 16195467
Cell Calcium. 2010 Jan;47(1):1-10
pubmed: 19945161
J Am Soc Echocardiogr. 2016 Nov;29(11):1056-1065
pubmed: 27641101
Nature. 1999 Jan 21;397(6716):259-63
pubmed: 9930701
Cell Calcium. 2014 Dec;56(6):482-92
pubmed: 25459299
J Biol Chem. 1995 May 12;270(19):11678-83
pubmed: 7744807
Am J Physiol Cell Physiol. 2012 Jan 15;302(2):C405-11
pubmed: 22031597
BMB Rep. 2014 Feb;47(2):69-79
pubmed: 24411466
J Mol Cell Cardiol. 2011 Jul;51(1):58-66
pubmed: 21382375
Adv Biol Regul. 2015 Jan;57:217-27
pubmed: 25497594
Cell Calcium. 2013 Aug;54(2):111-9
pubmed: 23747049
J Biol Chem. 2014 Mar 28;289(13):9380-95
pubmed: 24558039
Biochem Biophys Res Commun. 2007 Nov 23;363(3):656-61
pubmed: 17904526
FEBS Lett. 2015 Feb 27;589(5):608-14
pubmed: 25643985
Am J Physiol Heart Circ Physiol. 2018 Mar 1;314(3):H542-H551
pubmed: 29146614
Adv Biol Regul. 2018 May;68:88-96
pubmed: 29217255
Am J Physiol Heart Circ Physiol. 2006 Apr;290(4):H1660-70
pubmed: 16272207
Am J Physiol. 1999 May;276(5):L868-74
pubmed: 10330043
Am J Physiol Cell Physiol. 2012 Dec 1;303(11):C1156-72
pubmed: 23034388
J Clin Invest. 2014 Nov;124(11):4773-80
pubmed: 25329695
Front Physiol. 2018 May 07;9:486
pubmed: 29867539
Blood. 2011 Mar 10;117(10):2924-34
pubmed: 21193695
Biochem J. 2011 Jun 1;436(2):231-9
pubmed: 21568942
Circ Res. 2004 Sep 3;95(5):496-505
pubmed: 15256480
Pulm Circ. 2011 Winter;1(1):84-94
pubmed: 21709766
Gen Physiol Biophys. 2012 Jun;31(2):119-30
pubmed: 22781815
BMJ. 2018 Mar 14;360:j5492
pubmed: 29540357
Am J Physiol Heart Circ Physiol. 2012 Jun 1;302(11):H2190-210
pubmed: 22447942
Circ Res. 2010 Sep 3;107(5):659-66
pubmed: 20616315