End-stage kidney disease in infancy: an educational review.
Chronic hemodialysis
Chronic peritoneal dialysis
Growth
Hemodialysis
Infants
Neonates
Nutrition
Pediatric ESKD
Peritoneal dialysis
Journal
Pediatric nephrology (Berlin, Germany)
ISSN: 1432-198X
Titre abrégé: Pediatr Nephrol
Pays: Germany
ID NLM: 8708728
Informations de publication
Date de publication:
02 2020
02 2020
Historique:
received:
06
07
2018
accepted:
12
11
2018
revised:
05
11
2018
pubmed:
23
11
2018
medline:
16
1
2021
entrez:
23
11
2018
Statut:
ppublish
Résumé
An increasing number of infants with end-stage kidney disease (ESKD) are surviving and receiving renal replacement therapy (RRT). Unique clinical issues specific to this age group of patients influence their short- and long-term outcomes. This review summarizes current epidemiology, clinical characteristics, ethical dilemmas, management concerns, and outcomes of infants requiring chronic dialysis therapy. Optimal care during infancy requires a multidisciplinary team working closely with the patient's family. Nutritional management, infection prevention, and attention to cardiovascular status are important treatment targets. Although mortality rates remain higher among infants on dialysis compared to older pediatric dialysis patients, outcomes have improved over time. Most importantly, infants who subsequently receive a kidney transplant are now experiencing graft survival rates that are comparable to older pediatric patients.
Identifiants
pubmed: 30465082
doi: 10.1007/s00467-018-4151-8
pii: 10.1007/s00467-018-4151-8
pmc: PMC6529305
mid: NIHMS1514176
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
229-240Subventions
Organisme : NCATS NIH HHS
ID : KL2 TR001109
Pays : United States
Organisme : NCATS NIH HHS
ID : KL2 TR002490
Pays : United States
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