Amniotic-Derived Treatments and Formulations.

Amnion Animals Cartilage Diseases / therapy Humans Osteoarthritis / therapy Randomized Controlled Trials as Topic Sports Medicine / trends Tendon Injuries / therapy
Allograft Amniotic fluid Amniotic membrane Sports medicine injury Tissue regeneration

Journal

Clinics in sports medicine
ISSN: 1556-228X
Titre abrégé: Clin Sports Med
Pays: United States
ID NLM: 8112473

Informations de publication

Date de publication:
Jan 2019
Historique:
entrez: 24 11 2018
pubmed: 24 11 2018
medline: 14 12 2018
Statut: ppublish

Résumé

In orthopedic sports medicine, amniotic-derived products have demonstrated promising preclinical and early clinical results for the treatment of tendon/ligament injuries, cartilage defects, and osteoarthritis. The amniotic membrane is a metabolically active tissue that has demonstrated anti-inflammatory, antimicrobial, antifibrotic, and epithelialization-promoting features that make it uniquely suited for several clinical applications. Although the existing clinical literature is limited, there are several ongoing clinical trials aiming to elucidate the specific applications and benefits of these products. This article reviews the current amniotic-derived treatment options and the existing literature on outcomes, complications, and safety profile of these products for use in sports medicine.

Identifiants

DOI: 10.1016/j.csm.2018.08.002 PMID: 30466722
pubmed: 30466722
pii: S0278-5919(18)30074-7
doi: 10.1016/j.csm.2018.08.002
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

45-59

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Robert A Duerr (RA)

Department of Orthopedic surgery, Jameson Crane Sports Medicine Institute, Ohio State University, 2835 Fred Taylor Drive, Columbus, OH 43202, USA. Electronic address: robbie.duerr@gmail.com.

Jakob Ackermann (J)

Department of Orthopedic Surgery, Brigham & Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.

Andreas H Gomoll (AH)

Department of Orthopedic surgery, Hospital for Special Surgery, Weill-Cornell Medical School, 535 East 70th Street, New York, NY 10021, USA.

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Classifications MeSH

questionsmedicales.fr › Structures de l'embryon › Embryon de mammifère › Membranes extraembryonnaires › Amnios › Amniotic-Derived Treatments and Formulations.
questionsmedicales.fr › Eucaryotes › Animaux › Amniotic-Derived Treatments and Formulations.
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies du tissu conjonctif › Maladies du cartilage › Amniotic-Derived Treatments and Formulations.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Amniotic-Derived Treatments and Formulations.
questionsmedicales.fr › Maladies ostéomusculaires › Arthrose › Amniotic-Derived Treatments and Formulations.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études cliniques comme sujet › Essais cliniques comme sujet › Essais cliniques contrôlés comme sujet › Essais contrôlés randomisés comme sujet › Amniotic-Derived Treatments and Formulations.
questionsmedicales.fr › Professions de santé › Médecine › Médecine du sport › Amniotic-Derived Treatments and Formulations.
questionsmedicales.fr › Plaies et blessures › Traumatismes des tendons › Amniotic-Derived Treatments and Formulations.