Newborn Screening for Severe Combined Immunodeficiency in the United States: Lessons Learned.
Hematopoietic cell transplant (HCT)
Newborn screen (NBS)
Severe combined immunodeficiency (SCID)
T-cell lymphopenia
T-cell receptor excision circles (TRECs)
Journal
Immunology and allergy clinics of North America
ISSN: 1557-8607
Titre abrégé: Immunol Allergy Clin North Am
Pays: United States
ID NLM: 8805635
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
entrez:
24
11
2018
pubmed:
24
11
2018
medline:
18
12
2019
Statut:
ppublish
Résumé
In the United States, significant improvement in diagnosis and outcomes for children affected with severe combined immunodeficiency has followed institution of newborn screening using an assay to measure T-cell receptor excision circles in newborn dried blood spot specimens. Key to this outcome is the avoidance of infectious complications in infants with severe combined immunodeficiency.
Identifiants
pubmed: 30466767
pii: S0889-8561(18)30072-9
doi: 10.1016/j.iac.2018.08.002
pii:
doi:
Substances chimiques
Receptors, Antigen, T-Cell
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1-11Subventions
Organisme : NIGMS NIH HHS
ID : R01 GM107132
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI105776
Pays : United States
Organisme : NIAID NIH HHS
ID : U54 AI082973
Pays : United States
Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.