Prevalence and correlates of growth failure in young African patients with sickle cell disease.
Africa
SCD complications
Sickle cell disease
growth
haemolysis
Journal
British journal of haematology
ISSN: 1365-2141
Titre abrégé: Br J Haematol
Pays: England
ID NLM: 0372544
Informations de publication
Date de publication:
01 2019
01 2019
Historique:
received:
22
05
2018
accepted:
06
09
2018
pubmed:
24
11
2018
medline:
19
9
2019
entrez:
24
11
2018
Statut:
ppublish
Résumé
Growth failure (GF) in children with sickle cell disease (SCD) tends to decline in high-income countries, but data are lacking in sub-Saharan Africa. We performed a cross-sectional study nested in the CADRE (Cœur, Artères et DREpanocytose) cohort in Mali, Senegal, Cameroon, Gabon and the Ivory Coast. SCD patients and healthy controls aged 5-21 years old were recruited (n = 2583). Frequency of GF, defined as a height, weight or body mass index below the 5th percentile on World health Organization growth charts, was calculated. We assessed associations between GF and SCD phenotypic group, clinical and biological characteristics and history of SCD-related complications. GF was diagnosed in 51% of HbSS, 58% of HbSβ
Substances chimiques
Hemoglobin, Sickle
0
Types de publication
Clinical Trial
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
253-262Informations de copyright
© 2018 British Society for Haematology and John Wiley & Sons Ltd.