Spontaneous outbreak of Astragalus pehuenches (Fabaceae) poisoning in cattle in Argentina.


Journal

Toxicon : official journal of the International Society on Toxinology
ISSN: 1879-3150
Titre abrégé: Toxicon
Pays: England
ID NLM: 1307333

Informations de publication

Date de publication:
Jan 2019
Historique:
received: 24 09 2018
revised: 08 11 2018
accepted: 19 11 2018
pubmed: 24 11 2018
medline: 12 1 2019
entrez: 24 11 2018
Statut: ppublish

Résumé

This is the first report of a spontaneous outbreak of Astragalus pehuenches poisoning on a farm in Argentine Patagonia, where 63 out of 70 cattle died. The main clinical signs of affected animals were ataxia, balance loss and progressive emaciation. Purkinje cells presented vacuolation and marginalization of the nucleus. Astragalus pehuenches was detected in the paddock as well as in the ruminal content and fecal matter samples of the affected animals. Swainsonine concentrations in Astragalus specimens were found to be as high as 0.096%.

Identifiants

pubmed: 30468758
pii: S0041-0101(18)31024-9
doi: 10.1016/j.toxicon.2018.11.303
pii:
doi:

Substances chimiques

Swainsonine RSY4RK37KQ

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

84-86

Informations de copyright

Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Auteurs

Agustin Martinez (A)

Grupo Salud Animal, Instituto Nacional de Tecnología Agropecuaria (INTA), Modesta Victoria 4450, 8400 Bariloche, Argentina. Electronic address: martinez.agustin@inta.gob.ar.

Catalina Lauroua (C)

Residencia estudiantil, Universidad Nacional del Centro de la Provincia de Buenos Aires, Argentina.

Laura B Borrelli (LB)

Laboratorio de Microhistología, INTA Bariloche, Argentina.

Dale R Gardner (DR)

Poisonous Plant Research Laboratory, ARS-USDA, United States.

Carlos A Robles (CA)

Grupo Salud Animal, Instituto Nacional de Tecnología Agropecuaria (INTA), Modesta Victoria 4450, 8400 Bariloche, Argentina.

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Classifications MeSH