Obesity, but not metabolic syndrome, as a risk factor for late-onset asthma in Japanese women.
Health insurance claims
Late-onset asthma
Metabolic syndrome
Obesity
Specific health checkups
Journal
Allergology international : official journal of the Japanese Society of Allergology
ISSN: 1440-1592
Titre abrégé: Allergol Int
Pays: England
ID NLM: 9616296
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
11
08
2018
revised:
18
10
2018
accepted:
25
10
2018
pubmed:
27
11
2018
medline:
2
8
2019
entrez:
27
11
2018
Statut:
ppublish
Résumé
Several cross-sectional studies have suggested an association between obesity and asthma. However, few studies have investigated this relationship longitudinally, especially in middle-aged subjects. Although metabolic syndrome is a well-known risk factor for many non-communicable diseases, its contribution to asthma remains controversial. From 2008, specific health checkups for metabolic syndrome have been conducted throughout Japan. To seek relationships of obesity and metabolic syndrome with late-onset asthma in Japan, we analyzed data collected from health insurance claims and specific health checkups for metabolic syndrome at three large health insurance societies. Among subjects aged 40-64 years (n = 9888), multivariate logistic regression analyses were performed to investigate the relationships of obesity and metabolic syndrome in fiscal year 2012 (from April 2012 to March 2013) with the incidence of late-onset asthma in the following two years (from April 2013 to March 2015). In women, BMI 25-29.9 kg/m Only the obesity measures, not metabolic syndrome, were shown to be significant risk factors for the incidence of late-onset asthma but only in middle-aged Japanese women, and not in men.
Sections du résumé
BACKGROUND
BACKGROUND
Several cross-sectional studies have suggested an association between obesity and asthma. However, few studies have investigated this relationship longitudinally, especially in middle-aged subjects. Although metabolic syndrome is a well-known risk factor for many non-communicable diseases, its contribution to asthma remains controversial.
METHODS
METHODS
From 2008, specific health checkups for metabolic syndrome have been conducted throughout Japan. To seek relationships of obesity and metabolic syndrome with late-onset asthma in Japan, we analyzed data collected from health insurance claims and specific health checkups for metabolic syndrome at three large health insurance societies. Among subjects aged 40-64 years (n = 9888), multivariate logistic regression analyses were performed to investigate the relationships of obesity and metabolic syndrome in fiscal year 2012 (from April 2012 to March 2013) with the incidence of late-onset asthma in the following two years (from April 2013 to March 2015).
RESULTS
RESULTS
In women, BMI 25-29.9 kg/m
CONCLUSIONS
CONCLUSIONS
Only the obesity measures, not metabolic syndrome, were shown to be significant risk factors for the incidence of late-onset asthma but only in middle-aged Japanese women, and not in men.
Identifiants
pubmed: 30473411
pii: S1323-8930(18)30157-6
doi: 10.1016/j.alit.2018.10.003
pii:
doi:
Types de publication
Journal Article
Langues
eng
Pagination
240-246Informations de copyright
Copyright © 2018 Japanese Society of Allergology. Production and hosting by Elsevier B.V. All rights reserved.