Detection of recombinant and endogenous mouse melatonin receptors by monoclonal antibodies targeting the C-terminal domain.

Animals Antibodies, Monoclonal / immunology Antibody Specificity / immunology Mice Protein Domains Receptor, Melatonin, MT1 / analysis Receptor, Melatonin, MT2 / analysis
G protein-coupled receptor melatonin melatonin receptor monoclonal antibodies

Journal

Journal of pineal research
ISSN: 1600-079X
Titre abrégé: J Pineal Res
Pays: England
ID NLM: 8504412

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 12 09 2018
revised: 04 11 2018
accepted: 16 11 2018
pubmed: 27 11 2018
medline: 24 5 2019
entrez: 27 11 2018
Statut: ppublish

Résumé

Melatonin receptors play important roles in the regulation of circadian and seasonal rhythms, sleep, retinal functions, the immune system, depression, and type 2 diabetes development. Melatonin receptors are approved drug targets for insomnia, non-24-hour sleep-wake disorders, and major depressive disorders. In mammals, two melatonin receptors (MTRs) exist, MT

Identifiants

DOI: 10.1111/jpi.12540 PMID: 30475390
pubmed: 30475390
doi: 10.1111/jpi.12540
doi:

Substances chimiques

Antibodies, Monoclonal 0
Receptor, Melatonin, MT1 0
Receptor, Melatonin, MT2 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e12540

Subventions

Organisme : Bundesministerium für Bildung und Forschung
Organisme : Fondation pour la Recherche Médicale
ID : Equipe FRM DEQ20130326503
Organisme : Institut National de la Santé et de la Recherche Médicale
Organisme : Agence Nationale de la Recherche
ID : ANR-11-LABX-0071
Organisme : Agence Nationale de la Recherche
ID : ANR-12-RPIB-0016 "MED-HET-REC-2"
Organisme : Agence Nationale de la Recherche
ID : ANR-2011-BSV1-012-01 "MLT2D"
Organisme : Agence Nationale de la Recherche
ID : ANR-DFG 2011 "MELA-BETES"
Organisme : Centre National de la Recherche Scientifique

Informations de copyright

© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Auteurs

Erika Cecon (E)

Inserm U1016, Institut Cochin, Paris, France.
CNRS UMR 8104, Paris, France.
Sorbonne Paris Cité, Univ. Paris Descartes, Paris, France.

Anna Ivanova (A)

Molecular Diabetology, Faculty of Medicine, University Hospital, TU Dresden, Dresden, Germany.
Faculty of Medicine, Paul Langerhans Institute Dresden (PLID) of the Helmholtz Center Munich at University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany.
German Center for Diabetes Research (DZD), Munich Neuherberg, Germany.

Marine Luka (M)

Inserm U1016, Institut Cochin, Paris, France.
CNRS UMR 8104, Paris, France.
Sorbonne Paris Cité, Univ. Paris Descartes, Paris, France.

Florence Gbahou (F)

Inserm U1016, Institut Cochin, Paris, France.
CNRS UMR 8104, Paris, France.
Sorbonne Paris Cité, Univ. Paris Descartes, Paris, France.

Anne Friederich (A)

Molecular Diabetology, Faculty of Medicine, University Hospital, TU Dresden, Dresden, Germany.
Faculty of Medicine, Paul Langerhans Institute Dresden (PLID) of the Helmholtz Center Munich at University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany.
German Center for Diabetes Research (DZD), Munich Neuherberg, Germany.

Jean-Luc Guillaume (JL)

Inserm U1016, Institut Cochin, Paris, France.
CNRS UMR 8104, Paris, France.
Sorbonne Paris Cité, Univ. Paris Descartes, Paris, France.

Patrick Keller (P)

Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Dresden, Germany.

Klaus Knoch (K)

Molecular Diabetology, Faculty of Medicine, University Hospital, TU Dresden, Dresden, Germany.
Faculty of Medicine, Paul Langerhans Institute Dresden (PLID) of the Helmholtz Center Munich at University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany.
German Center for Diabetes Research (DZD), Munich Neuherberg, Germany.

Raise Ahmad (R)

Inserm U1016, Institut Cochin, Paris, France.
CNRS UMR 8104, Paris, France.
Sorbonne Paris Cité, Univ. Paris Descartes, Paris, France.

Philippe Delagrange (P)

Pôle d'Innovation Thérapeutique Neuropsychiatrie, Institut de Recherches Servier, Croissy, France.

Michele Solimena (M)

Molecular Diabetology, Faculty of Medicine, University Hospital, TU Dresden, Dresden, Germany.
Faculty of Medicine, Paul Langerhans Institute Dresden (PLID) of the Helmholtz Center Munich at University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany.
German Center for Diabetes Research (DZD), Munich Neuherberg, Germany.
Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Dresden, Germany.

Ralf Jockers (R)

Inserm U1016, Institut Cochin, Paris, France.
CNRS UMR 8104, Paris, France.
Sorbonne Paris Cité, Univ. Paris Descartes, Paris, France.
ORCID: 0000-0002-4354-1750

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Detection of recombinant and endogenous mouse...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps monoclonaux › Detection of recombinant and endogenous mouse...
questionsmedicales.fr › Phénomènes du système immunitaire › Spécificité des anticorps › Detection of recombinant and endogenous mouse...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Detection of recombinant and endogenous mouse...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure tertiaire des protéines › Domaines protéiques › Detection of recombinant and endogenous mouse...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs couplés aux protéines G › Récepteur de la mélatonine de type MT1 › Detection of recombinant and endogenous mouse...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs couplés aux protéines G › Récepteur de la mélatonine de type MT2 › Detection of recombinant and endogenous mouse...