[Accidental intoxication by outdoor and garden plants : Data from two German poison centres].

Akzidentelle Vergiftungen mit Gartenpflanzen und Pflanzen in der freien Natur : Daten aus zwei deutschen Giftinformationszentren.

Journal

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
ISSN: 1437-1588
Titre abrégé: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
Pays: Germany
ID NLM: 101181368

Informations de publication

Date de publication:
Jan 2019
Historique:
pubmed: 28 11 2018
medline: 13 9 2019
entrez: 28 11 2018
Statut: ppublish

Résumé

Accidental exposure of children to plants occurs often and results in numerous calls to poison centres. The aim of this study was to identify outdoor plants that led to moderate or severe poisoning after accidental exposure and to identify patterns of paediatric plant exposures. Human exposure data on accidental exposures provided by two German poison centres were retrospectively evaluated regarding the number and the routes of exposure. Special attention was turned to the kind and severity of symptoms. Based on these data a modified Litovitz factor was calculated. Out of 42,344 confirmed exposures to 227 plant species, 39,346 (93%) were asymptomatic, 2415 (5.7%) experienced minor, 580 (1.3%) moderate and 3 (0.007%) severe symptoms. Twenty-six plant genera were responsible for 70% of all exposures. Only eight of these plants (Arum spec., Laburnum anagyroides, Narcissus spec., Phaseolus vulgaris/coccineus, Prunus laurocerasus, Sambucus spec., Taxus baccata, Thuja spec.) led to at least moderate symptoms. Accidental exposure of children aged 0.5-5 years was mainly by oral ingestion (98%) and involved mostly fruits (60%). Exposure data collected by poison centres are very useful for hazard identification of outdoor plants. The data give a comprehensive overview of observed symptoms, which offers valuable instruments for use in clinical practice.

Sections du résumé

BACKGROUND AND OBJECTIVES OBJECTIVE
Accidental exposure of children to plants occurs often and results in numerous calls to poison centres. The aim of this study was to identify outdoor plants that led to moderate or severe poisoning after accidental exposure and to identify patterns of paediatric plant exposures.
MATERIALS AND METHODS METHODS
Human exposure data on accidental exposures provided by two German poison centres were retrospectively evaluated regarding the number and the routes of exposure. Special attention was turned to the kind and severity of symptoms. Based on these data a modified Litovitz factor was calculated.
RESULTS RESULTS
Out of 42,344 confirmed exposures to 227 plant species, 39,346 (93%) were asymptomatic, 2415 (5.7%) experienced minor, 580 (1.3%) moderate and 3 (0.007%) severe symptoms. Twenty-six plant genera were responsible for 70% of all exposures. Only eight of these plants (Arum spec., Laburnum anagyroides, Narcissus spec., Phaseolus vulgaris/coccineus, Prunus laurocerasus, Sambucus spec., Taxus baccata, Thuja spec.) led to at least moderate symptoms. Accidental exposure of children aged 0.5-5 years was mainly by oral ingestion (98%) and involved mostly fruits (60%).
CONCLUSIONS CONCLUSIONS
Exposure data collected by poison centres are very useful for hazard identification of outdoor plants. The data give a comprehensive overview of observed symptoms, which offers valuable instruments for use in clinical practice.

Identifiants

pubmed: 30478484
doi: 10.1007/s00103-018-2853-5
pii: 10.1007/s00103-018-2853-5
doi:

Types de publication

Journal Article

Langues

ger

Sous-ensembles de citation

IM

Pagination

73-83

Auteurs

Maren Hermanns-Clausen (M)

Vergiftungs-Informations-Zentrale, Klinik für allgemeine Kinder und Jugendmedizin, Zentrum für Kinder- und Jugendmedizin (Departement), Universitätsklinikum Freiburg, Mathildenstr. 1, 79106, Freiburg, Deutschland. maren.hermanns-clausen@uniklinik-freiburg.de.

Ingrid Koch (I)

Charité - Universitätsmedizin Berlin, Giftnotruf, Berlin, Deutschland.

Jörg Pietsch (J)

Abteilung Toxikologische Chemie, Institut für Rechtsmedizin, Technische Universität Dresden, Dresden, Deutschland.

Hilke Andresen-Streichert (H)

Arbeitsbereich Toxikologie, Institut für Rechtsmedizin, Uniklinik Köln, Köln, Deutschland.

Kathrin Begemann (K)

Abteilung Exposition, Bundesinstitut für Risikobewertung, Berlin, Deutschland.

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Classifications MeSH