Challenges in the Polyene- and Azole-Based Pharmacotherapy of Ocular Fungal Infections.

Animals Antifungal Agents / administration & dosage Azoles / administration & dosage Eye Infections, Fungal / drug therapy Humans Microbial Sensitivity Tests Ophthalmic Solutions / administration & dosage Polyenes / administration & dosage
anti-infectives keratitis ocular fungal infections ocular pharmacotherapy polyene and azole antifungals

Journal

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
ISSN: 1557-7732
Titre abrégé: J Ocul Pharmacol Ther
Pays: United States
ID NLM: 9511091

Informations de publication

Date de publication:
Historique:
pubmed: 28 11 2018
medline: 7 7 2020
entrez: 28 11 2018
Statut: ppublish

Résumé

Polyenes and azoles constitute 2 major drug classes in the antifungal armamentarium used to treat fungal infections of the eye such as fungal keratitis, endophthalmitis, conjunctivitis, and blepharitis. These classes of drugs have come to occupy an important niche in ophthalmic antifungal therapy due to their broad spectrum of activity against a variety of filamentous and yeast-like fungi. Natamycin suspension (Natacyn

Identifiants

DOI: 10.1089/jop.2018.0089 PMID: 30481082 PMC: PMC6354613
pubmed: 30481082
doi: 10.1089/jop.2018.0089
pmc: PMC6354613
doi:

Substances chimiques

Antifungal Agents 0
Azoles 0
Ophthalmic Solutions 0
Polyenes 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

6-22

Subventions

Organisme : NIGMS NIH HHS
ID : P20 GM104932
Pays : United States

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Auteurs

Prit Lakhani (P)

1 Department of Pharmaceutics and Drug Delivery, School of Pharmacy, University of Mississippi, Oxford, Mississippi.
2 Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, Oxford, Mississippi.

Akash Patil (A)

1 Department of Pharmaceutics and Drug Delivery, School of Pharmacy, University of Mississippi, Oxford, Mississippi.
2 Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, Oxford, Mississippi.

Soumyajit Majumdar (S)

1 Department of Pharmaceutics and Drug Delivery, School of Pharmacy, University of Mississippi, Oxford, Mississippi.
2 Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, Oxford, Mississippi.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Challenges in the Polyene- and Azole-Based...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antifongiques › Challenges in the Polyene- and Azole-Based...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Challenges in the Polyene- and Azole-Based...
questionsmedicales.fr › Maladies de l'oeil › Infections de l'oeil › Mycoses oculaires › Challenges in the Polyene- and Azole-Based...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Challenges in the Polyene- and Azole-Based...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Challenges in the Polyene- and Azole-Based...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Solutions pharmaceutiques › Solutions ophtalmiques › Challenges in the Polyene- and Azole-Based...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures acycliques › Alcènes › Polyènes › Challenges in the Polyene- and Azole-Based...