Dietary ursolic acid improves health span and life span in male Drosophila melanogaster.

Animal Feed Animals Drosophila Proteins / metabolism Drosophila melanogaster Longevity / drug effects Male Triterpenes / administration & dosage Ursolic Acid
healthy aging secondary plant compounds triterpenoids

Journal

BioFactors (Oxford, England)
ISSN: 1872-8081
Titre abrégé: Biofactors
Pays: Netherlands
ID NLM: 8807441

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 04 09 2018
accepted: 26 09 2018
pubmed: 30 11 2018
medline: 23 7 2019
entrez: 30 11 2018
Statut: ppublish

Résumé

The health and life span of Drosophila melanogaster are partly determined by intestinal barrier integrity, metabolic rate as well as stress response and the expression of longevity-associated genes, depending on genetic and dietary factors. Ursolic acid (UA) is a naturally occurring triterpenoid exhibiting potential antimicrobial, anti-inflammatory, and antiobesity activity and counteracting age-related deficits in muscle strength. In this study, UA was dietarily administered to w

Identifiants

DOI: 10.1002/biof.1467 PMID: 30496629
pubmed: 30496629
doi: 10.1002/biof.1467
doi:

Substances chimiques

Drosophila Proteins 0
Triterpenes 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

169-186

Subventions

Organisme : Deutsche Forschungsgemeinschaft/German Research Foundation
ID : STA 1509/2-1

Commentaires et corrections

Type : ErratumIn

Informations de copyright

© 2018 International Union of Biochemistry and Molecular Biology.

Auteurs

Stefanie Staats (S)

Institute of Human Nutrition and Food Science, University of Kiel, Kiel, Germany.

Anika E Wagner (AE)

Institute of Nutritional Medicine, University of Lübeck, Lübeck, Germany.

Kai Lüersen (K)

Institute of Human Nutrition and Food Science, University of Kiel, Kiel, Germany.

Axel Künstner (A)

Group for Medical Systems Biology, Lübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.
Institute for Cardiogenetics, University of Lübeck, Lübeck, Germany.

Timo Meyer (T)

Institute of Human Nutrition and Food Science, University of Kiel, Kiel, Germany.

Anna K Kahns (AK)

Institute of Human Nutrition and Food Science, University of Kiel, Kiel, Germany.

Stefanie Derer (S)

Institute of Nutritional Medicine, University of Lübeck, Lübeck, Germany.

Simon Graspeuntner (S)

Department of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.

Jan Rupp (J)

Department of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.

Hauke Busch (H)

Group for Medical Systems Biology, Lübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.
Institute for Cardiogenetics, University of Lübeck, Lübeck, Germany.

Christian Sina (C)

Institute of Nutritional Medicine, University of Lübeck, Lübeck, Germany.

Ignacio R Ipharraguerre (IR)

Institute of Human Nutrition and Food Science, University of Kiel, Kiel, Germany.

Gerald Rimbach (G)

Institute of Human Nutrition and Food Science, University of Kiel, Kiel, Germany.

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Classifications MeSH

questionsmedicales.fr › Aliments et boissons › Aliments › Produits agricoles › Aliment pour animaux › Dietary ursolic acid improves health span and...
questionsmedicales.fr › Eucaryotes › Animaux › Dietary ursolic acid improves health span and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines d'arthropode › Protéines d'insecte › Protéines de Drosophila › Dietary ursolic acid improves health span and...
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Arthropodes › Insectes › Pterygota › Neoptera › Holometabola › Diptera › Drosophilidae › Drosophila › Drosophila melanogaster › Dietary ursolic acid improves health span and...
questionsmedicales.fr › Phénomènes physiologiques › Longévité › Dietary ursolic acid improves health span and...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Triterpènes › Dietary ursolic acid improves health span and...