Medicines associated with folate-homocysteine-methionine pathway disruption.


Journal

Archives of toxicology
ISSN: 1432-0738
Titre abrégé: Arch Toxicol
Pays: Germany
ID NLM: 0417615

Informations de publication

Date de publication:
02 2019
Historique:
received: 08 09 2018
accepted: 20 11 2018
pubmed: 1 12 2018
medline: 19 5 2020
entrez: 1 12 2018
Statut: ppublish

Résumé

Folate is vital for cell development and growth. It is involved in one-carbon transfer reactions essential for the synthesis of purines and pyrimidines. It also acts in conjunction with cobalamin (vitamin B

Identifiants

pubmed: 30499019
doi: 10.1007/s00204-018-2364-z
pii: 10.1007/s00204-018-2364-z
doi:

Substances chimiques

Enzyme Inhibitors 0
Folic Acid Antagonists 0
Homocysteine 0LVT1QZ0BA
Folic Acid 935E97BOY8
Methionine AE28F7PNPL
Tetrahydrofolate Dehydrogenase EC 1.5.1.3
Thymidylate Synthase EC 2.1.1.45

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

227-251

Subventions

Organisme : Javna Agencija za Raziskovalno Dejavnost RS
ID : P3-0124
Pays : International

Auteurs

M Vidmar (M)

Research Unit, Department of Obstetrics and Gynecology, University Medical Centre Ljubljana, Šlajmarjeva 3, Ljubljana, Slovenia.
University of Ljubljana, Faculty of Pharmacy, Aškerčeva 7, Ljubljana, Slovenia.

J Grželj (J)

University of Ljubljana, Faculty of Pharmacy, Aškerčeva 7, Ljubljana, Slovenia.
Krka, d.d., Novo mesto, Šmarješka 6, Novo mesto, Slovenia.

I Mlinarič-Raščan (I)

University of Ljubljana, Faculty of Pharmacy, Aškerčeva 7, Ljubljana, Slovenia.

K Geršak (K)

Research Unit, Department of Obstetrics and Gynecology, University Medical Centre Ljubljana, Šlajmarjeva 3, Ljubljana, Slovenia.

M Sollner Dolenc (MS)

University of Ljubljana, Faculty of Pharmacy, Aškerčeva 7, Ljubljana, Slovenia. marija.sollner@ffa.uni-lj.si.

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Classifications MeSH