Ebola Virus Infection Associated with Transmission from Survivors.
Ebola virus disease
Guinea
Liberia
Sierra Leone
West Africa
response
sexual transmission
surveillance
survivors
viral persistence
viruses
Journal
Emerging infectious diseases
ISSN: 1080-6059
Titre abrégé: Emerg Infect Dis
Pays: United States
ID NLM: 9508155
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
pubmed:
1
12
2018
medline:
30
7
2019
entrez:
1
12
2018
Statut:
ppublish
Résumé
Ebola virus (EBOV) can persist in immunologically protected body sites in survivors of Ebola virus disease, creating the potential to initiate new chains of transmission. From the outbreak in West Africa during 2014-2016, we identified 13 possible events of viral persistence-derived transmission of EBOV (VPDTe) and applied predefined criteria to classify transmission events based on the strength of evidence for VPDTe and source and route of transmission. For 8 events, a recipient case was identified; possible source cases were identified for 5 of these 8. For 5 events, a recipient case or chain of transmission could not be confidently determined. Five events met our criteria for sexual transmission (male-to-female). One VPDTe event led to at least 4 generations of cases; transmission was limited after the other events. VPDTe has increased the importance of Ebola survivor services and sustained surveillance and response capacity in regions with previously widespread transmission.
Identifiants
pubmed: 30500321
doi: 10.3201/eid2502.181011
pmc: PMC6346469
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Pagination
249-255Références
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