Developmental disorders and malformations of the breast.


Journal

Seminars in diagnostic pathology
ISSN: 0740-2570
Titre abrégé: Semin Diagn Pathol
Pays: United States
ID NLM: 8502262

Informations de publication

Date de publication:
Jan 2019
Historique:
pubmed: 7 12 2018
medline: 30 11 2019
entrez: 4 12 2018
Statut: ppublish

Résumé

Developmental abnormalities and malformations of the breast are rare and encompass a variety of genetic, syndromic, acquired and sporadic conditions. Abnormalities in development may include irregularities in the nipple areolar complex and/or the underlying glandular tissue, resulting in under or overdevelopment of breasts. Age of presentation and clinical severity is dependent on the underlying biologic cause. Abnormalities may involve the entirety of unilateral or bilateral breasts, particularly in association with syndromic conditions or endocrine abnormalities. Disordered development may also be focal, resulting in tumor-like lesions such as hamartomas, pseudoangiomatous stromal hyperplasia and gynecomastia. In this review, we discuss the disorders of breast development including etiologies, clinical presentations and corresponding histopathologic features.

Identifiants

pubmed: 30503250
pii: S0740-2570(18)30117-5
doi: 10.1053/j.semdp.2018.11.007
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

11-15

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Emily Reisenbichler (E)

Department of Pathology, Yale School of Medicine, Yale New Haven Hospital, 310 Cedar St, New Haven, CT 06510, United States.

Krisztina Z Hanley (KZ)

Department of Pathology, Emory University Hospital, Atlanta, GA 30322, United States. Electronic address: khanley@emory.edu.

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Classifications MeSH