Localizing Proton-Mediated Inhibitory Feedback at the Retinal Horizontal Cell-Cone Synapse with Genetically-Encoded pH Probes.
Animals
Calcium Channels, L-Type
/ genetics
Connexins
/ metabolism
Feedback, Physiological
/ physiology
Female
Glutamates
/ physiology
Hydrogen-Ion Concentration
Male
Protons
Receptors, AMPA
/ metabolism
Retinal Cone Photoreceptor Cells
/ physiology
Retinal Horizontal Cells
/ physiology
Synapses
/ physiology
Synaptic Transmission
/ physiology
Vesicle-Associated Membrane Protein 2
/ genetics
Zebrafish
fluorescent protein
lateral inhibition
pHluorin
photoreceptor
retina
synaptic transmission
Journal
The Journal of neuroscience : the official journal of the Society for Neuroscience
ISSN: 1529-2401
Titre abrégé: J Neurosci
Pays: United States
ID NLM: 8102140
Informations de publication
Date de publication:
23 01 2019
23 01 2019
Historique:
received:
14
06
2018
revised:
12
11
2018
accepted:
17
11
2018
pubmed:
7
12
2018
medline:
18
12
2019
entrez:
4
12
2018
Statut:
ppublish
Résumé
Lateral inhibition in the vertebrate retina depends on a negative feedback synapse between horizontal cells (HCs) and rod and cone photoreceptors. A change in pH is thought to be the signal for negative feedback, but its spatial profile in the synaptic cleft is unknown. Here we use three different membrane proteins, each fused to the same genetically-encoded pH-sensitive Green Fluorescent Protein (GFP) (pHluorin), to probe synaptic pH in retina from transgenic zebrafish (
Identifiants
pubmed: 30504272
pii: JNEUROSCI.1541-18.2018
doi: 10.1523/JNEUROSCI.1541-18.2018
pmc: PMC6343651
doi:
Substances chimiques
Calcium Channels, L-Type
0
Connexins
0
Glutamates
0
Protons
0
Receptors, AMPA
0
Vesicle-Associated Membrane Protein 2
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
651-662Subventions
Organisme : NEI NIH HHS
ID : F32 EY020095
Pays : United States
Organisme : NEI NIH HHS
ID : P30 EY003176
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY024334
Pays : United States
Informations de copyright
Copyright © 2019 the authors 0270-6474/19/390651-12$15.00/0.
Références
Dev Cell. 2006 Jun;10(6):839-50
pubmed: 16740485
J Neurosci. 2008 Jan 9;28(2):456-64
pubmed: 18184788
Biomed Eng Online. 2003 May 17;2:13
pubmed: 12801419
J Neurosci. 2011 Mar 23;31(12):4397-406
pubmed: 21430141
Neuron. 2001 Dec 20;32(6):1107-17
pubmed: 11754841
Curr Biol. 2017 Dec 4;27(23):3603-3615.e5
pubmed: 29174891
Invest Ophthalmol Vis Sci. 2007 Feb;48(2):522-9
pubmed: 17251445
Vis Neurosci. 1990 Dec;5(6):571-83
pubmed: 2085473
J Chem Neuroanat. 2009 Jul;37(4):254-65
pubmed: 19481010
J Comp Neurol. 2002 Nov 4;453(1):100-11
pubmed: 12357435
J Physiol. 1968 Aug;197(3):551-66
pubmed: 5666169
Cell Rep. 2016 Feb 16;14(6):1369-1381
pubmed: 26854222
Nature. 1998 Jul 9;394(6689):192-5
pubmed: 9671304
PLoS Biol. 2011 May;9(5):e1001057
pubmed: 21559323
J Neurophysiol. 2004 Jun;91(6):2404-12
pubmed: 14960560
Nature. 1995 Dec 14;378(6558):730-3
pubmed: 7501021
J Neurosci. 2012 Nov 14;32(46):16314-30
pubmed: 23152615
Prog Retin Eye Res. 2012 Sep;31(5):407-41
pubmed: 22580106
J Comp Neurol. 2013 Aug 1;521(11):2486-501
pubmed: 23296739
Science. 2001 May 11;292(5519):1178-80
pubmed: 11349152
J Physiol. 1982 Feb;323:211-27
pubmed: 6808119
Dev Dyn. 2007 Nov;236(11):3088-99
pubmed: 17937395
Mol Cell Neurosci. 2013 Sep;56:384-92
pubmed: 23911793
Cold Spring Harb Symp Quant Biol. 1965;30:559-66
pubmed: 5219504
PLoS Biol. 2015 Dec 10;13(12):e1002322
pubmed: 26656622
Prog Neurobiol. 1990;34(5):401-27
pubmed: 2192394
J Comp Neurol. 2008 Jan 10;506(2):328-38
pubmed: 18022944
PLoS One. 2009 Jun 30;4(6):e6090
pubmed: 19564917
Nat Neurosci. 2001 Sep;4(9):917-26
pubmed: 11528423
J Neurosci. 2001 Apr 1;21(7):2488-500
pubmed: 11264323
Invest Ophthalmol Vis Sci. 2001 Sep;42(10):2414-8
pubmed: 11527958
J Gen Physiol. 2003 Dec;122(6):657-71
pubmed: 14610018
J Neurophysiol. 1991 May;65(5):1197-206
pubmed: 1651374
J Physiol. 2016 Nov 15;594(22):6661-6677
pubmed: 27345444
Vis Neurosci. 2011 Mar;28(2):137-44
pubmed: 21324227
Vision Res. 1986;26(1):33-44
pubmed: 3012877
Neuron. 2000 Mar;25(3):635-47
pubmed: 10774731
Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):7035-40
pubmed: 10359834
Front Cell Neurosci. 2017 Jul 11;11:198
pubmed: 28744203
J Neurophysiol. 2006 Mar;95(3):1992-5
pubmed: 16371457
Glia. 2005 Jan 15;49(2):184-96
pubmed: 15390100
Neuron. 2006 Jun 15;50(6):823-39
pubmed: 16772166
Nat Neurosci. 2014 Feb;17(2):262-8
pubmed: 24441679
J Neurochem. 2010 Oct;115(1):102-11
pubmed: 20633206
Neuron. 2004 Mar 4;41(5):755-66
pubmed: 15003175
Nat Cell Biol. 2000 Apr;2(4):197-204
pubmed: 10783237
Vision Res. 1996 Dec;36(24):3943-53
pubmed: 9068848
J Comp Neurol. 2007 Apr 10;501(5):765-79
pubmed: 17299759
J Neurosci. 1996 Nov 1;16(21):6713-21
pubmed: 8824312
J Comp Neurol. 2009 Dec 10;517(5):633-44
pubmed: 19827152
J Neurosci. 2016 Sep 28;36(39):10075-88
pubmed: 27683904
Pflugers Arch. 1990 Oct;417(2):234-9
pubmed: 2084617
Neuron. 2000 Jul;27(1):85-95
pubmed: 10939333
Neuron. 2000 Dec;28(3):857-72
pubmed: 11163272
J Neurosci. 2005 Apr 20;25(16):4108-17
pubmed: 15843613
Front Mol Neurosci. 2017 Dec 07;10:403
pubmed: 29375296
J Cell Biol. 1975 Apr;65(1):192-222
pubmed: 1127010
J Neurosci. 2011 Sep 21;31(38):13431-41
pubmed: 21940436
J Gen Physiol. 2007 Aug;130(2):169-82
pubmed: 17664345
J Neurosci. 2004 Jun 2;24(22):5172-6
pubmed: 15175386
PLoS Biol. 2014 May 20;12(5):e1001864
pubmed: 24844296
J Neurosci. 2006 May 10;26(19):5028-36
pubmed: 16687494