Ultrasonographic Findings of Uterine Carcinosarcoma.
Adult
CA-125 Antigen
/ blood
Carcinosarcoma
/ diagnostic imaging
Female
Humans
Membrane Proteins
/ blood
Menstruation Disturbances
Middle Aged
Myometrium
/ diagnostic imaging
Postmenopause
Retrospective Studies
Ultrasonography
Uterine Hemorrhage
Uterine Neoplasms
/ diagnostic imaging
Uterus
/ diagnostic imaging
Vaginal Discharge
Color Doppler flow imaging
Color Doppler ultrasound
Diagnosis
Transvaginal ultrasound
Uterine carcinosarcoma
Vaginal bleeding
Journal
Gynecologic and obstetric investigation
ISSN: 1423-002X
Titre abrégé: Gynecol Obstet Invest
Pays: Switzerland
ID NLM: 7900587
Informations de publication
Date de publication:
2019
2019
Historique:
received:
28
06
2016
accepted:
28
09
2017
pubmed:
7
12
2018
medline:
6
8
2019
entrez:
4
12
2018
Statut:
ppublish
Résumé
The aim of this study was to investigate the clinical features and ultrasonographic findings of uterine carcinosarcoma (UCS). Seventy-five patients (mean age, 58.6 years) with pathologically proven UCS who were treated at our hospital from January 2003 to December 2015 were retrospectively recruited. The clinical features and preoperative findings on transvaginal sonography (TVS) were investigated. Eighty percent of the patients were postmenopausal. The primary symptoms were postmenopausal abnormal uterine bleeding (57.3%), irregular menstruation (18.7%), vaginal discharge (10.7%) and the presence of a uterine mass or others (13.3%). The tumor marker CA125 was evaluated in 43 women and was found to be elevated in 15 (34.9%); in 60% of those women (9/15), the CA125 level was lower than 200U/ml. According to the frequency of the different types of lesions observed by ultrasonic imaging, we decided to categorize the lesions into 3 different groups as follows: Group I, intrauterine tumors (73.33%); group II, intra-myometrial tumors (13.33%); and group III, intra-endometrial tumors (13.33 %). Combined with the clinical features, the characteristics demonstrated by TVS provide evidence for an indication of the presence of UCS and could contribute to clinical decision-making.
Identifiants
pubmed: 30504724
pii: 000481885
doi: 10.1159/000481885
doi:
Substances chimiques
CA-125 Antigen
0
MUC16 protein, human
0
Membrane Proteins
0
Types de publication
Journal Article
Langues
eng
Pagination
277-282Informations de copyright
© 2018 S. Karger AG, Basel.