Ultrasonographic Findings of Uterine Carcinosarcoma.


Journal

Gynecologic and obstetric investigation
ISSN: 1423-002X
Titre abrégé: Gynecol Obstet Invest
Pays: Switzerland
ID NLM: 7900587

Informations de publication

Date de publication:
2019
Historique:
received: 28 06 2016
accepted: 28 09 2017
pubmed: 7 12 2018
medline: 6 8 2019
entrez: 4 12 2018
Statut: ppublish

Résumé

The aim of this study was to investigate the clinical features and ultrasonographic findings of uterine carcinosarcoma (UCS). Seventy-five patients (mean age, 58.6 years) with pathologically proven UCS who were treated at our hospital from January 2003 to December 2015 were retrospectively recruited. The clinical features and preoperative findings on transvaginal sonography (TVS) were investigated. Eighty percent of the patients were postmenopausal. The primary symptoms were postmenopausal abnormal uterine bleeding (57.3%), irregular menstruation (18.7%), vaginal discharge (10.7%) and the presence of a uterine mass or others (13.3%). The tumor marker CA125 was evaluated in 43 women and was found to be elevated in 15 (34.9%); in 60% of those women (9/15), the CA125 level was lower than 200U/ml. According to the frequency of the different types of lesions observed by ultrasonic imaging, we decided to categorize the lesions into 3 different groups as follows: Group I, intrauterine tumors (73.33%); group II, intra-myometrial tumors (13.33%); and group III, intra-endometrial tumors (13.33 %). Combined with the clinical features, the characteristics demonstrated by TVS provide evidence for an indication of the presence of UCS and could contribute to clinical decision-making.

Identifiants

pubmed: 30504724
pii: 000481885
doi: 10.1159/000481885
doi:

Substances chimiques

CA-125 Antigen 0
MUC16 protein, human 0
Membrane Proteins 0

Types de publication

Journal Article

Langues

eng

Pagination

277-282

Informations de copyright

© 2018 S. Karger AG, Basel.

Auteurs

Fangui Zhao (F)

Department of Ultrasonic Diagnosis, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.

Yang Xu (Y)

Department of Ultrasonic Diagnosis, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.

Hao Zhang (H)

Department of Pathology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.

Yunyun Ren (Y)

Department of Ultrasonic Diagnosis, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China, renyunyun1181@163.com.

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Classifications MeSH