Where cone snails and spiders meet: design of small cyclic sodium-channel inhibitors.

Animals Oocytes / metabolism Peptides / pharmacology Snails / metabolism Sodium Channel Blockers / pharmacology Spider Venoms / metabolism Spiders / metabolism Voltage-Gated Sodium Channel Blockers / pharmacology Voltage-Gated Sodium Channels / metabolism Xenopus laevis / metabolism
peptide cyclization peptide toxin toxin-based therapeutics voltage-gated sodium channel

Journal

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
ISSN: 1530-6860
Titre abrégé: FASEB J
Pays: United States
ID NLM: 8804484

Informations de publication

Date de publication:
03 2019
Historique:
pubmed: 5 12 2018
medline: 13 11 2019
entrez: 5 12 2018
Statut: ppublish

Résumé

A 13 aa residue voltage-gated sodium (Na

Identifiants

DOI: 10.1096/fj.201801909R PMID: 30509130
pubmed: 30509130
doi: 10.1096/fj.201801909R
doi:

Substances chimiques

Peptides 0
Sodium Channel Blockers 0
Spider Venoms 0
Voltage-Gated Sodium Channel Blockers 0
Voltage-Gated Sodium Channels 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3693-3703

Auteurs

Steve Peigneur (S)

Toxicology and Pharmacology, Katholieke Universiteit (KU) Leuven, Campus Gasthuisberg, Leuven, Belgium.
Department de Bioquímica e Imunologia, Laboratório de Venenos e Toxinas Animais, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo-Horizonte, Brazil.

Olivier Cheneval (O)

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.

Mohitosh Maiti (M)

Laboratory of Medicinal Chemistry, Rega Institute for Medical Research, Katholieke Universiteit (KU) Leuven, Leuven, Belgium.

Enrico Leipold (E)

Department of Biophysics, Center for Molecular Biomedicine, Jena University Hospital, Friedrich Schiller University Jena, Germany.

Stefan H Heinemann (SH)

Department of Biophysics, Center for Molecular Biomedicine, Jena University Hospital, Friedrich Schiller University Jena, Germany.

Eveline Lescrinier (E)

Laboratory of Medicinal Chemistry, Rega Institute for Medical Research, Katholieke Universiteit (KU) Leuven, Leuven, Belgium.

Piet Herdewijn (P)

Laboratory of Medicinal Chemistry, Rega Institute for Medical Research, Katholieke Universiteit (KU) Leuven, Leuven, Belgium.

Maria Elena De Lima (ME)

Department de Bioquímica e Imunologia, Laboratório de Venenos e Toxinas Animais, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo-Horizonte, Brazil.
Programa de Pós-Graduação em Ciências da Saúde, Biomedicina e Medicina, Instituto de Ensino e Pesquisa da Santa Casa de Belo Horizonte, Grupo Santa Casa de Belo Horizonte, Belo Horizonte, Brazil.

David J Craik (DJ)

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.

Christina I Schroeder (CI)

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.

Jan Tytgat (J)

Toxicology and Pharmacology, Katholieke Universiteit (KU) Leuven, Campus Gasthuisberg, Leuven, Belgium.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Where cone snails and spiders meet: design of...
questionsmedicales.fr › Cellules › Cellules germinales › Ovocytes › Where cone snails and spiders meet: design of...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Where cone snails and spiders meet: design of...
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Mollusca › Gastropoda › Escargots › Where cone snails and spiders meet: design of...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents cardiovasculaires › Bloqueurs de canaux sodiques › Where cone snails and spiders meet: design of...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Venins › Venins d'arthropode › Venins d'araignée › Where cone snails and spiders meet: design of...
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Arthropodes › Arachnida › Araignées › Where cone snails and spiders meet: design of...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents cardiovasculaires › Bloqueurs de canaux sodiques › Bloqueurs de canaux sodiques voltage-dépendants › Where cone snails and spiders meet: design of...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Canaux sodiques voltage-dépendants › Where cone snails and spiders meet: design of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Amphibiens › Anura › Pipidae › Xenopus › Xenopus laevis › Where cone snails and spiders meet: design of...