Solitary Bone Metastasis as the First Presentation of Germ Cell Testicular Cancer Treated with Internal Hemipelvectomy: A Case Report.
Adult
Antineoplastic Combined Chemotherapy Protocols
/ therapeutic use
Biopsy
Bleomycin
/ therapeutic use
Bone Neoplasms
/ diagnosis
Cisplatin
/ therapeutic use
Etoposide
/ therapeutic use
Hemipelvectomy
Humans
Male
Neoplasm Metastasis
Neoplasm, Residual
Neoplasms, Germ Cell and Embryonal
/ drug therapy
Orchiectomy
Pelvic Bones
/ pathology
Testicular Neoplasms
/ drug therapy
Treatment Outcome
Bone metastasis
En bloc resection
Internal hemipelvectomy
Testicular tumor
Journal
Urologia internationalis
ISSN: 1423-0399
Titre abrégé: Urol Int
Pays: Switzerland
ID NLM: 0417373
Informations de publication
Date de publication:
2019
2019
Historique:
received:
06
07
2018
accepted:
05
11
2018
pubmed:
5
12
2018
medline:
13
2
2020
entrez:
5
12
2018
Statut:
ppublish
Résumé
Solitary bone metastasis from testicular tumor is rare. In literature, only few cases of isolated bone metastasis at first presentation have been reported, and none of them have been treated with extended surgery of the pelvic bone. Case Presentation: We report the case of a 33-year-old man with an iliac bone osteolytic metastasis as the first presentation of a non-seminomatous germ-cell testis tumor (NSGCT), treated with post-chemotherapy en bloc resection of residual tumor in the left iliac bone (Type I + II internal hemipelvectomy). After a 72-month follow-up, the patient has been asymptomatic, with no signs of local recurrence or metastasis and negative serum tumor markers. Conclusions: In selected cases, testicular NSGCT with iliac bone metastasis and normal or normalizing tumor markers can be treated, in association with chemotherapy, by extended surgery, including bone resection, to obtain gain in survival and maintain limb function.
Identifiants
pubmed: 30513517
pii: 000495143
doi: 10.1159/000495143
doi:
Substances chimiques
Bleomycin
11056-06-7
Etoposide
6PLQ3CP4P3
Cisplatin
Q20Q21Q62J
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
116-119Informations de copyright
© 2018 S. Karger AG, Basel.