P
acylation
arylation
indoles
methylation
olefination
Journal
Angewandte Chemie (International ed. in English)
ISSN: 1521-3773
Titre abrégé: Angew Chem Int Ed Engl
Pays: Germany
ID NLM: 0370543
Informations de publication
Date de publication:
28 Jan 2019
28 Jan 2019
Historique:
received:
18
11
2018
pubmed:
7
12
2018
medline:
7
12
2018
entrez:
7
12
2018
Statut:
ppublish
Résumé
Rhodium-catalyzed C7-selective decarbonylative arylation, olefination, and methylation of indoles with carboxylic acids or anhydrides by C-H and C-C bond activation have been developed. Furthermore, C7-acylation products can also be generated selectively at a lower reaction temperature in the developed system. The key to the high reactivity and regioselectivity of this transformation is the appropriate choice of an indole N-PtBu
Identifiants
pubmed: 30520246
doi: 10.1002/anie.201813182
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1504-1508Subventions
Organisme : NSF of China
ID : Grant 2167020084
Informations de copyright
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.