Implementation of Clinical Proteomics: A Step Closer to Personalized Medicine?
biomarker validation
clinical proteomics
data sharing
implementation
Journal
Proteomics. Clinical applications
ISSN: 1862-8354
Titre abrégé: Proteomics Clin Appl
Pays: Germany
ID NLM: 101298608
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
received:
19
09
2018
revised:
23
11
2018
pubmed:
7
12
2018
medline:
3
5
2019
entrez:
7
12
2018
Statut:
ppublish
Résumé
The success of clinical proteomics, per definition, is ultimately defined by the clinical implementation of proteomics findings. Extensive research activity in the field, targeting especially biomarker discovery, has been conducted in the past decades, with several studies suggesting a benefit from proteome-based application in patient management. This viewpoint article discusses the current status in clinical proteomics with respect to implementation (as evidenced by the use of protein findings in drug labeling and patient stratification), and proposes specific action points for accelerating the biomarker validation process, placing special emphasis on the importance of data and resource sharing.
Identifiants
pubmed: 30520267
doi: 10.1002/prca.201800088
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e1800088Informations de copyright
© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.