Mixed-charge pseudo-zwitterionic mesoporous silica nanoparticles with low-fouling and reduced cell uptake properties.
Antimicrobial properties
Levofloxacin release
Low-fouling properties
Macrophage uptake
Mesoporous silica nanoparticles
Mixed-charge brushes
Pseudo-zwitterionic surface
Journal
Acta biomaterialia
ISSN: 1878-7568
Titre abrégé: Acta Biomater
Pays: England
ID NLM: 101233144
Informations de publication
Date de publication:
15 01 2019
15 01 2019
Historique:
received:
27
07
2018
revised:
26
11
2018
accepted:
05
12
2018
pubmed:
12
12
2018
medline:
23
2
2020
entrez:
12
12
2018
Statut:
ppublish
Résumé
The design of drug delivery systems needs to consider biocompatibility and host body recognition for an adequate actuation. In this work, mesoporous silica nanoparticles (MSNs) surfaces were successfully modified with two silane molecules to provide mixed-charge brushes (-NH
Identifiants
pubmed: 30529082
pii: S1742-7061(18)30737-2
doi: 10.1016/j.actbio.2018.12.012
pmc: PMC6718287
mid: EMS83665
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Silanes
0
Levofloxacin
6GNT3Y5LMF
Silicon Dioxide
7631-86-9
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
317-327Subventions
Organisme : European Research Council
ID : 694160
Pays : International
Informations de copyright
Copyright © 2018 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
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