Gene expression profiles of putative biomarkers in juvenile loggerhead sea turtles (Caretta caretta) exposed to polycyclic aromatic hydrocarbons.


Journal

Environmental pollution (Barking, Essex : 1987)
ISSN: 1873-6424
Titre abrégé: Environ Pollut
Pays: England
ID NLM: 8804476

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 28 06 2018
revised: 16 11 2018
accepted: 28 11 2018
pubmed: 12 12 2018
medline: 20 3 2019
entrez: 12 12 2018
Statut: ppublish

Résumé

There is evidence that polycyclic aromatic hydrocarbons (PAHs) are consistently the predominant organic contaminants in concentration found in loggerhead sea turtles (Caretta caretta) from the North and Central Adriatic Sea. Hence this study investigates the PAH toxicity to loggerheads by using a particular set of genes [i.e. CYP1B, CAT, GPX, GSTT1, SOD3, DNMT1, Epoxide hydrolase 1 (EPHX1), Poly (ADP-ribose) polymerase 1 (PARP1), Lamin-A/C isoform 3 (LMNA), Talin 1 (TLN1), Annexin A1 (ANXA1)] whose altered expression is potentially dependent on and specific for the PAH-related mechanism of action. Twenty healthy juvenile loggerheads were thus divided into high and low exposure groups (mean of ΣPAHs: 80.34 ng mL

Identifiants

pubmed: 30529946
pii: S0269-7491(18)32963-4
doi: 10.1016/j.envpol.2018.11.098
pii:
doi:

Substances chimiques

Environmental Biomarkers 0
Polycyclic Aromatic Hydrocarbons 0
Water Pollutants, Chemical 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

99-106

Informations de copyright

Copyright © 2018 Elsevier Ltd. All rights reserved.

Auteurs

Paolo Cocci (P)

School of Biosciences and Veterinary Medicine, University of Camerino, Via Gentile III Da Varano, I-62032, Camerino, MC, Italy.

Gilberto Mosconi (G)

School of Biosciences and Veterinary Medicine, University of Camerino, Via Gentile III Da Varano, I-62032, Camerino, MC, Italy.

Francesco Alessandro Palermo (FA)

School of Biosciences and Veterinary Medicine, University of Camerino, Via Gentile III Da Varano, I-62032, Camerino, MC, Italy. Electronic address: francesco.palermo@unicam.it.

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Classifications MeSH