Endonuclease Activity Inhibition of the NS1 Protein of Parvovirus B19 as a Novel Target for Antiviral Drug Development.
Antiviral Agents
/ pharmacology
Cell Line
DNA Replication
/ drug effects
DNA, Viral
/ genetics
Drug Development
Erythroid Precursor Cells
Humans
Parvoviridae Infections
/ drug therapy
Parvovirus B19, Human
/ drug effects
Viral Nonstructural Proteins
/ antagonists & inhibitors
Virus Replication
/ drug effects
antivirals
in vitro nicking assay
parvovirus B19
Journal
Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
received:
05
09
2018
accepted:
30
11
2018
pubmed:
12
12
2018
medline:
13
2
2020
entrez:
12
12
2018
Statut:
epublish
Résumé
Human parvovirus B19 (B19V), a member of the genus
Identifiants
pubmed: 30530599
pii: AAC.01879-18
doi: 10.1128/AAC.01879-18
pmc: PMC6395930
pii:
doi:
Substances chimiques
Antiviral Agents
0
DNA, Viral
0
NS1 protein, parvovirus
0
Viral Nonstructural Proteins
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIAID NIH HHS
ID : R01 AI070723
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI104494
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI124672
Pays : United States
Informations de copyright
Copyright © 2019 American Society for Microbiology.
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