Extracellular protons accelerate hERG channel deactivation by destabilizing voltage sensor relaxation.

Animals ERG1 Potassium Channel / chemistry Humans Ion Channel Gating Membrane Potentials Protein Domains Protons Xenopus

Journal

The Journal of general physiology
ISSN: 1540-7748
Titre abrégé: J Gen Physiol
Pays: United States
ID NLM: 2985110R

Informations de publication

Date de publication:
04 02 2019
Historique:
received: 04 06 2018
revised: 23 08 2018
accepted: 07 11 2018
pubmed: 12 12 2018
medline: 1 5 2020
entrez: 12 12 2018
Statut: ppublish

Résumé

hERG channels underlie the delayed-rectifier K

Identifiants

DOI: 10.1085/jgp.201812137 PMID: 30530765 PMC: PMC6363419
pubmed: 30530765
pii: jgp.201812137
doi: 10.1085/jgp.201812137
pmc: PMC6363419
doi:

Substances chimiques

ERG1 Potassium Channel 0
KCNH2 protein, human 0
Protons 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

231-246

Informations de copyright

© 2019 Shi et al.

Références

Biophys J. 2015 Mar 24;108(6):1435-1447
pubmed: 25809256
Nat Commun. 2015 Mar 30;6:6672
pubmed: 25818916
Biophys J. 2017 Jan 24;112(2):300-312
pubmed: 28122216
J Physiol. 1999 Feb 1;514 ( Pt 3):667-75
pubmed: 9882738
Nature. 1996 Feb 29;379(6568):833-6
pubmed: 8587608
J Gen Physiol. 2018 Jun 4;150(6):863-881
pubmed: 29743298
J Gen Physiol. 2011 May;137(5):455-72
pubmed: 21518834
J Gen Physiol. 2000 Nov;116(5):663-78
pubmed: 11055995
Pflugers Arch. 2018 Mar;470(3):517-536
pubmed: 29270671
Eur Biophys J. 2014 Mar;43(2-3):59-69
pubmed: 24362825
Biophys J. 2010 Nov 3;99(9):2841-52
pubmed: 21044581
J Gen Physiol. 2012 Sep;140(3):293-306
pubmed: 22891279
J Neurosci. 2007 Jan 10;27(2):270-8
pubmed: 17215386
Am J Physiol Cell Physiol. 2012 Jun 15;302(12):C1797-806
pubmed: 22517356
Biophys J. 1999 Jul;77(1):282-98
pubmed: 10388757
J Gen Physiol. 2012 Nov;140(5):481-93
pubmed: 23071266
Biophys J. 2011 Mar 2;100(5):L28-30
pubmed: 21354387
J Gen Physiol. 2000 Jun;115(6):749-58
pubmed: 10828248
J Cardiovasc Electrophysiol. 2010 Oct;21(10):1160-9
pubmed: 20455975
PLoS One. 2011;6(9):e24674
pubmed: 21935437
J Gen Physiol. 1996 May;107(5):611-9
pubmed: 8740374
Nature. 2008 Dec 18;456(7224):891-7
pubmed: 19092925
Channels (Austin). 2016;10(3):202-13
pubmed: 26794852
Cell Biochem Biophys. 2003;39(3):183-93
pubmed: 14716075
Nat Struct Mol Biol. 2010 Jul;17(7):869-875
pubmed: 20543828
Cardiovasc Res. 1994 Sep;28(9):1312-9
pubmed: 7954638
PLoS One. 2011 Jan 13;6(1):e16191
pubmed: 21249148
Cell Physiol Biochem. 2008;21(1-3):37-46
pubmed: 18209470
Channels (Austin). 2007 Nov-Dec;1(6):429-37
pubmed: 18690045
Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11648-53
pubmed: 23801759
Mol Membr Biol. 2009 Dec;26(8):435-47
pubmed: 19878047
Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H1710-8
pubmed: 20363888
Neuron. 1995 Jun;14(6):1293-301
pubmed: 7605638
PLoS One. 2013;8(3):e59265
pubmed: 23555008
Eur Biophys J. 2009 Jun;38(5):569-76
pubmed: 19172259
Physiol Rev. 2000 Apr;80(2):555-92
pubmed: 10747201
Pflugers Arch. 2015 Aug;467(8):1747-56
pubmed: 25224286
Channels (Austin). 2010 Sep-Oct;4(5):422-8
pubmed: 20935453
Pflugers Arch. 2014 Oct;466(10):1911-9
pubmed: 24407947
Cell. 1998 Nov 25;95(5):649-55
pubmed: 9845367
J Gen Physiol. 2009 May;133(5):467-83
pubmed: 19398775
J Physiol. 1998 Mar 15;507 ( Pt 3):631-8
pubmed: 9508824
J Gen Physiol. 2004 Oct;124(4):349-56
pubmed: 15365092
Biophys J. 2013 Nov 19;105(10):2312-22
pubmed: 24268143
J Biol Chem. 2006 May 5;281(18):12858-64
pubmed: 16524878
J Gen Physiol. 2003 Jun;121(6):599-614
pubmed: 12771194
J Physiol. 1988 Apr;398:441-73
pubmed: 2455801
J Physiol. 2001 Dec 15;537(Pt 3):843-51
pubmed: 11744759
J Mol Cell Cardiol. 2000 Jan;32(1):11-21
pubmed: 10652186
J Gen Physiol. 2013 Jun;141(6):721-35
pubmed: 23712551
Am J Physiol. 1999 Oct;277(4):H1283-92
pubmed: 10516162
J Membr Biol. 2005 Oct;207(3):169-81
pubmed: 16550488
Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17600-7
pubmed: 18818307
J Gen Physiol. 2010 Aug;136(2):203-24
pubmed: 20660661
J Biol Chem. 2014 Sep 12;289(37):25822-32
pubmed: 25074935
Biophys J. 2014 Oct 7;107(7):1564-72
pubmed: 25296308
Biophys J. 1999 Nov;77(5):2534-41
pubmed: 10545354
Cell. 2017 Apr 20;169(3):422-430.e10
pubmed: 28431243
J Gen Physiol. 1998 Nov;112(5):637-47
pubmed: 9806971
J Gen Physiol. 2004 Dec;124(6):703-18
pubmed: 15545400
J Physiol. 2005 Sep 15;567(Pt 3):737-55
pubmed: 15975984
PLoS One. 2012;7(2):e31640
pubmed: 22359612
J Physiol. 2004 Jul 15;558(Pt 2):417-31
pubmed: 15181157
J Gen Physiol. 1999 Apr;113(4):565-80
pubmed: 10102937
J Physiol. 2006 Sep 1;575(Pt 2):417-31
pubmed: 16777944
J Gen Physiol. 2013 Sep;142(3):289-303
pubmed: 23980197
Sheng Li Xue Bao. 2010 Feb 25;62(1):1-13
pubmed: 20179882
Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10534-9
pubmed: 12928493
Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2208-12
pubmed: 8700910
J Biol Chem. 1999 Apr 9;274(15):10113-8
pubmed: 10187793
Cell. 1995 Mar 10;80(5):795-803
pubmed: 7889573
Channels (Austin). 2014;8(1):84-9
pubmed: 24126078
Pflugers Arch. 1999 Aug;438(3):419-22
pubmed: 10398876
J Neurosci. 2001 Jun 15;21(12):4143-53
pubmed: 11404399
Cell Signal. 2012 Aug;24(8):1592-8
pubmed: 22522181
PLoS One. 2010 May 28;5(5):e10876
pubmed: 20526358
Science. 2010 Apr 2;328(5974):67-73
pubmed: 20360102
J Gen Physiol. 2011 Mar;137(3):315-25
pubmed: 21357734
Cell. 1995 Apr 21;81(2):299-307
pubmed: 7736582
Biochem J. 2013 May 1;451(3):463-74
pubmed: 23418776
Can J Physiol Pharmacol. 1987 Apr;65(4):681-5
pubmed: 2440542
J Biol Chem. 2007 Nov 2;282(44):31972-81
pubmed: 17823114

Auteurs

Yu Patrick Shi (YP)

Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada.

Samrat Thouta (S)

Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada.

Yen May Cheng (YM)

Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada.

Tom W Claydon (TW)

Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada thomas_claydon@sfu.ca.
ORCID: 0000-0002-5143-7451

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Extracellular protons accelerate hERG channel...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux potassiques › Canaux potassiques voltage-dépendants › Canaux potassiques éther-à-go-go › Canal potassique ERG1 › Extracellular protons accelerate hERG channel...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Extracellular protons accelerate hERG channel...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes électrophysiologiques › Ouverture et fermeture des portes des canaux ioniques › Extracellular protons accelerate hERG channel...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Potentiels de membrane › Extracellular protons accelerate hERG channel...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure tertiaire des protéines › Domaines protéiques › Extracellular protons accelerate hERG channel...
questionsmedicales.fr › Phénomènes physiques › Particules élémentaires › Nucléons › Protons › Extracellular protons accelerate hERG channel...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Amphibiens › Anura › Pipidae › Xenopus › Extracellular protons accelerate hERG channel...