The Effects of Probiotic Supplementation on Genetic and Metabolic Profiles in Patients with Gestational Diabetes Mellitus: a Randomized, Double-Blind, Placebo-Controlled Trial.
Adult
Bifidobacterium bifidum
/ physiology
Blood Glucose
/ metabolism
Diabetes, Gestational
/ drug therapy
Double-Blind Method
Female
Humans
Insulin
/ blood
Lactobacillus acidophilus
/ physiology
Lacticaseibacillus casei
/ physiology
Lipids
/ blood
Malondialdehyde
/ metabolism
PPAR gamma
/ genetics
Pregnancy
Probiotics
/ administration & dosage
Transforming Growth Factor beta
/ genetics
Triglycerides
/ blood
Vascular Endothelial Growth Factor A
/ genetics
Young Adult
Gestational diabetes mellitus
Inflammation
Insulin resistance
Metabolic status
Probiotic supplementation
Journal
Probiotics and antimicrobial proteins
ISSN: 1867-1314
Titre abrégé: Probiotics Antimicrob Proteins
Pays: United States
ID NLM: 101484100
Informations de publication
Date de publication:
12 2019
12 2019
Historique:
pubmed:
12
12
2018
medline:
3
7
2020
entrez:
12
12
2018
Statut:
ppublish
Résumé
This study was carried out to evaluate the effects of probiotic supplementation on genetic and metabolic profiles in patients with gestational diabetes mellitus (GDM) who were not on oral hypoglycemic agents. This randomized, double-blind, placebo-controlled clinical trial was conducted in 48 patients with GDM. Participants were randomly divided into two groups to intake either probiotic capsule containing Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium bifidum, Lactobacillus fermentum (2 × 10
Identifiants
pubmed: 30535534
doi: 10.1007/s12602-018-9490-z
pii: 10.1007/s12602-018-9490-z
doi:
Substances chimiques
Blood Glucose
0
Insulin
0
Lipids
0
PPAR gamma
0
Transforming Growth Factor beta
0
Triglycerides
0
Vascular Endothelial Growth Factor A
0
Malondialdehyde
4Y8F71G49Q
Banques de données
IRCT
['IRCT20171010036697N1']
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1227-1235Références
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