Heme oxygenase-1 induction by hemin prevents oxidative stress-induced acute cholestasis in the rat.

Animals Antioxidants / pharmacology Bile / metabolism Bilirubin / metabolism Catalase / metabolism Cholestasis / chemically induced Disease Models, Animal Enzyme Induction Glutathione / metabolism Heme Oxygenase (Decyclizing) / biosynthesis Hemin / pharmacology Liver / drug effects Male Oxidative Stress Rats, Wistar Superoxide Dismutase / metabolism tert-Butylhydroperoxide
Bilirubin acute cholestasis heme oxygenase 1 hepatocanalicular transport oxidative stress

Journal

Clinical science (London, England : 1979)
ISSN: 1470-8736
Titre abrégé: Clin Sci (Lond)
Pays: England
ID NLM: 7905731

Informations de publication

Date de publication:
15 01 2019
Historique:
received: 01 08 2018
revised: 07 12 2018
accepted: 11 12 2018
pubmed: 13 12 2018
medline: 23 10 2019
entrez: 13 12 2018
Statut: epublish

Résumé

We previously demonstrated in

Identifiants

DOI: 10.1042/CS20180675 PMID: 30538149
pubmed: 30538149
pii: CS20180675
doi: 10.1042/CS20180675
doi:

Substances chimiques

Antioxidants 0
Hemin 743LRP9S7N
tert-Butylhydroperoxide 955VYL842B
Catalase EC 1.11.1.6
Heme Oxygenase (Decyclizing) EC 1.14.14.18
Hmox1 protein, rat EC 1.14.14.18
Superoxide Dismutase EC 1.15.1.1
Glutathione GAN16C9B8O
Bilirubin RFM9X3LJ49

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

117-134

Informations de copyright

© 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

Auteurs

Pamela L Martín (PL)

Instituto de Fisiología Experimental (IFISE-CONICET), Facultad de Ciencias Bioquímicas y Farmacéuticas (U.N.R.), Rosario, Argentina.

Paula Ceccatto (P)

Instituto de Fisiología Experimental (IFISE-CONICET), Facultad de Ciencias Bioquímicas y Farmacéuticas (U.N.R.), Rosario, Argentina.

María V Razori (MV)

Instituto de Fisiología Experimental (IFISE-CONICET), Facultad de Ciencias Bioquímicas y Farmacéuticas (U.N.R.), Rosario, Argentina.

Daniel E A Francés (DEA)

Instituto de Fisiología Experimental (IFISE-CONICET), Facultad de Ciencias Bioquímicas y Farmacéuticas (U.N.R.), Rosario, Argentina.

Sandra M M Arriaga (SMM)

Area Bioquímica Clínica, Facultad de Ciencias Bioquímicas y Farmacéuticas (U.N.R.), Rosario, Argentina.

Gerardo B Pisani (GB)

Area Morfología, Facultad de Ciencias Bioquímicas y Farmacéuticas (U.N.R.), Rosario, Argentina.

Alejandra I Martínez (AI)

Area Morfología, Facultad de Ciencias Bioquímicas y Farmacéuticas (U.N.R.), Rosario, Argentina.

Enrique J Sánchez Pozzi (EJ)

Instituto de Fisiología Experimental (IFISE-CONICET), Facultad de Ciencias Bioquímicas y Farmacéuticas (U.N.R.), Rosario, Argentina.

Marcelo G Roma (MG)

Instituto de Fisiología Experimental (IFISE-CONICET), Facultad de Ciencias Bioquímicas y Farmacéuticas (U.N.R.), Rosario, Argentina.

Cecilia L Basiglio (CL)

Instituto de Fisiología Experimental (IFISE-CONICET), Facultad de Ciencias Bioquímicas y Farmacéuticas (U.N.R.), Rosario, Argentina basiglio@ifise-conicet.gov.ar.
Area Bioquímica Clínica, Facultad de Ciencias Bioquímicas y Farmacéuticas (U.N.R.), Rosario, Argentina.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents protecteurs › Antioxydants › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Liquides et sécrétions biologiques › Sécrétions corporelles › Bile › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Facteurs biologiques › Pigments biologiques › Pigments biliaires › Bilirubine › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Peroxidases › Catalase › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladie des voies biliaires › Maladies des canaux biliaires › Cholestase › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Régulation de l'expression des gènes codant pour des enzymes › Induction enzymatique › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Oligopeptides › Glutathion › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Oxygénases › Mixed function oxygenases › Heme oxygenase (decyclizing) › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Facteurs biologiques › Pigments biologiques › Porphyrines › Métalloporphyrines › Hème › Hémine › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Système digestif › Foie › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Phénomènes physiologiques › Stress physiologique › Stress oxydatif › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Wistar › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Superoxide dismutase › Heme oxygenase-1 induction by hemin prevents...
questionsmedicales.fr › Composés chimiques organiques › Radicaux libres › Peroxydes › 2-Hydroperoxy-2-méthyl-propane › Heme oxygenase-1 induction by hemin prevents...