Impact of Spontaneous Breathing Trial on Work of Breathing Indices Derived From Esophageal Pressure, Electrical Activity of the Diaphragm, and Oxygen Consumption in Children.


Journal

Respiratory care
ISSN: 1943-3654
Titre abrégé: Respir Care
Pays: United States
ID NLM: 7510357

Informations de publication

Date de publication:
May 2019
Historique:
pubmed: 13 12 2018
medline: 6 5 2020
entrez: 13 12 2018
Statut: ppublish

Résumé

The present study aimed to characterize the behavior of 3 components of respiratory muscle function during mechanical ventilation weaning in children to better understand the respective impact of a spontaneous breathing trial on ventilatory mechanical action (esophageal pressure [P This was a prospective single-center study. All children > 1 months and <18 y old who were intubated and on mechanical ventilation, and who were hospitalized in the pediatric ICU were eligible. Subjects considered as ready to extubate were included. Simultaneous recordings of oxygen consumption, P Twenty subjects (median age, 5.5 mo) were included. Half of them were admitted for a respiratory cause. The increase in P In these children who were critically ill, a spontaneous breathing trial induced a moderate and nonsignificant increase in work of breathing, as reflected by the respiratory drive with EA

Sections du résumé

BACKGROUND BACKGROUND
The present study aimed to characterize the behavior of 3 components of respiratory muscle function during mechanical ventilation weaning in children to better understand the respective impact of a spontaneous breathing trial on ventilatory mechanical action (esophageal pressure [P
METHODS METHODS
This was a prospective single-center study. All children > 1 months and <18 y old who were intubated and on mechanical ventilation, and who were hospitalized in the pediatric ICU were eligible. Subjects considered as ready to extubate were included. Simultaneous recordings of oxygen consumption, P
RESULTS RESULTS
Twenty subjects (median age, 5.5 mo) were included. Half of them were admitted for a respiratory cause. The increase in P
CONCLUSIONS CONCLUSIONS
In these children who were critically ill, a spontaneous breathing trial induced a moderate and nonsignificant increase in work of breathing, as reflected by the respiratory drive with EA

Identifiants

pubmed: 30538160
pii: respcare.06351
doi: 10.4187/respcare.06351
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

509-518

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2019 by Daedalus Enterprises.

Auteurs

Guillaume Mortamet (G)

Pediatric Intensive Care Unit, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Montreal, Québec, Canada. mortam@hotmail.fr.
Université de Montréal, Montréal, Québec, Canada.
Université de Paris-Est, Créteil, France.
Unité Institut National de la Santé et de la Recherche Médicale (INSERM) U955, Créteil, France.

Nicolas Nardi (N)

Pediatric Intensive Care Unit, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Montreal, Québec, Canada.
Université de Montréal, Montréal, Québec, Canada.

Véronique Groleau (V)

Université de Montréal, Montréal, Québec, Canada.
Department of Gastroenterology, Hepatology and Nutrition, CHU Sainte-Justine, Montreal, Québec, Canada.

Sandrine Essouri (S)

Université de Montréal, Montréal, Québec, Canada.
Department of Pediatrics, CHU Sainte-Justine, Montreal, Québec, Canada.

Brigitte Fauroux (B)

Université de Montréal, Montréal, Québec, Canada.
Université de Paris-Est, Créteil, France.
Unité Institut National de la Santé et de la Recherche Médicale (INSERM) U955, Créteil, France.
Pediatric Noninvasive Ventilation and Sleep Unit, Hôpital Necker, Paris, France.

Philippe Jouvet (P)

Pediatric Intensive Care Unit, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Montreal, Québec, Canada.
Université de Montréal, Montréal, Québec, Canada.

Guillaume Emeriaud (G)

Pediatric Intensive Care Unit, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Montreal, Québec, Canada.
Université de Montréal, Montréal, Québec, Canada.

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Classifications MeSH