[Corneal dystrophies in optical coherence tomography].
Hornhautdystrophien in der optischen Kohärenztomographie.
Corneal dystrophy
Corneal opacity
Dystrophy
OCT
Optical coherence tomography
Journal
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
ISSN: 1433-0423
Titre abrégé: Ophthalmologe
Pays: Germany
ID NLM: 9206148
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
pubmed:
13
12
2018
medline:
7
9
2019
entrez:
13
12
2018
Statut:
ppublish
Résumé
Corneal optical coherence tomography (anterior segment OCT, AS-OCT) is described in the current IC3D classification of corneal dystrophies to be a method for improvement of clinical diagnostics and treatment. In this case series AS-OCT images of corneal dystrophies were analyzed with respect to morphological changes. This was a retrospective imaging and morphological case series with 38 eyes. For image acquisition the corneal module of the high-resolution spectral-domain OCT Zeiss Cirrus HD-5000 platform (Oberkochen, Germany) was employed. The following corneal dystrophies were analyzed: epithelial basement membrane dystrophy, Meesmann corneal dystrophy, Reis-Bücklers corneal dystrophy, granular corneal dystrophy type 1, granular corneal dystrophy type 2 and macular corneal dystrophy. The AS-OCT images showed the typical changes of the dystrophies through hyperreflectivity and hyporeflectivity in the individual corneal layers. The findings in the AS-OCT images correlated well with the histological descriptions in the literature and provided additional information to the slit lamp examination, especially with respect to the exact location of the alterations. Corneal AS-OCT imaging seems to be a helpful tool for determination of morphological changes in patients with corneal dystrophies and can facilitate both the diagnostics and surgical treatment decisions.
Sections du résumé
BACKGROUND
BACKGROUND
Corneal optical coherence tomography (anterior segment OCT, AS-OCT) is described in the current IC3D classification of corneal dystrophies to be a method for improvement of clinical diagnostics and treatment.
OBJECTIVE
OBJECTIVE
In this case series AS-OCT images of corneal dystrophies were analyzed with respect to morphological changes.
MATERIAL AND METHODS
METHODS
This was a retrospective imaging and morphological case series with 38 eyes. For image acquisition the corneal module of the high-resolution spectral-domain OCT Zeiss Cirrus HD-5000 platform (Oberkochen, Germany) was employed. The following corneal dystrophies were analyzed: epithelial basement membrane dystrophy, Meesmann corneal dystrophy, Reis-Bücklers corneal dystrophy, granular corneal dystrophy type 1, granular corneal dystrophy type 2 and macular corneal dystrophy.
RESULTS
RESULTS
The AS-OCT images showed the typical changes of the dystrophies through hyperreflectivity and hyporeflectivity in the individual corneal layers. The findings in the AS-OCT images correlated well with the histological descriptions in the literature and provided additional information to the slit lamp examination, especially with respect to the exact location of the alterations.
CONCLUSION
CONCLUSIONS
Corneal AS-OCT imaging seems to be a helpful tool for determination of morphological changes in patients with corneal dystrophies and can facilitate both the diagnostics and surgical treatment decisions.
Identifiants
pubmed: 30539228
doi: 10.1007/s00347-018-0832-8
pii: 10.1007/s00347-018-0832-8
doi:
Types de publication
Journal Article
Langues
ger
Sous-ensembles de citation
IM
Pagination
857-864Références
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