Synthesis and nitric oxide releasing properties of novel fluoro S-nitrosothiols.
Journal
Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838
Informations de publication
Date de publication:
02 Jan 2019
02 Jan 2019
Historique:
pubmed:
14
12
2018
medline:
14
12
2018
entrez:
14
12
2018
Statut:
ppublish
Résumé
A series of new fluoro S-nitrosothiols is reported as potential nitric oxide (NO) donors. A three-step synthesis and the NO releasing kinetic profiles of these species are presented. The stoichiometric release of NO, with the clean formation of corresponding disulfides, confirms that these new species can facilitate their application as NO donors for various applications including creating novel antimicrobial and thromboresistant fluoropolymer-based medical devices.
Identifiants
pubmed: 30542676
doi: 10.1039/c8cc08868c
pmc: PMC6380185
mid: NIHMS1002579
doi:
Types de publication
Journal Article
Langues
eng
Pagination
401-404Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL128337
Pays : United States
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