Melanoma tumour vasculature heterogeneity: from mice models to human.


Journal

Journal of cancer research and clinical oncology
ISSN: 1432-1335
Titre abrégé: J Cancer Res Clin Oncol
Pays: Germany
ID NLM: 7902060

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 05 09 2018
accepted: 30 11 2018
pubmed: 14 12 2018
medline: 8 3 2019
entrez: 15 12 2018
Statut: ppublish

Résumé

Tumour angiogenesis is defined by an anarchic vasculature and irregularities in alignment of endothelial cells. These structural abnormalities could explain the variability in distribution of nanomedicines in various tumour models. Then, the main goal of this study was to compare and to characterize the tumour vascular structure in different mouse models of melanoma tumours (B16F10 and SK-Mel-28) and in human melanomas from different patients. Tumours were obtained by subcutaneous injection of 10

Identifiants

pubmed: 30547320
doi: 10.1007/s00432-018-2809-z
pii: 10.1007/s00432-018-2809-z
doi:

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

589-597

Subventions

Organisme : Ligue Contre le Cancer
ID : 2016
Organisme : Erasmus+
ID : 2015

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Auteurs

Vincent Pautu (V)

UMR Inserm 1066, CNRS 6021, Université d'Angers, CHU, IBS, IRIS, MINT, UNIV Angers, INSERM, CNRS, Université Bretagne Loire, IBS-CHU, 4, rue Larrey, 49933, Angers, France.

Adélie Mellinger (A)

UMR Inserm 1066, CNRS 6021, Université d'Angers, CHU, IBS, IRIS, MINT, UNIV Angers, INSERM, CNRS, Université Bretagne Loire, IBS-CHU, 4, rue Larrey, 49933, Angers, France.

Pauline Resnier (P)

UMR Inserm 1066, CNRS 6021, Université d'Angers, CHU, IBS, IRIS, MINT, UNIV Angers, INSERM, CNRS, Université Bretagne Loire, IBS-CHU, 4, rue Larrey, 49933, Angers, France.

Elise Lepeltier (E)

UMR Inserm 1066, CNRS 6021, Université d'Angers, CHU, IBS, IRIS, MINT, UNIV Angers, INSERM, CNRS, Université Bretagne Loire, IBS-CHU, 4, rue Larrey, 49933, Angers, France.

Ludovic Martin (L)

CHU Angers, 4 rue Larrey, 49933, Angers, France.

Lise Boussemart (L)

Department of Dermatology, Pontchaillou Hospital, CHU de Rennes, 35000, Rennes, France.
Univ Rennes, CNRS, IGDR, UMR 6290, 35000, Rennes, France.

Franck Letournel (F)

UMR Inserm 1066, CNRS 6021, Université d'Angers, CHU, IBS, IRIS, MINT, UNIV Angers, INSERM, CNRS, Université Bretagne Loire, IBS-CHU, 4, rue Larrey, 49933, Angers, France.

Catherine Passirani (C)

UMR Inserm 1066, CNRS 6021, Université d'Angers, CHU, IBS, IRIS, MINT, UNIV Angers, INSERM, CNRS, Université Bretagne Loire, IBS-CHU, 4, rue Larrey, 49933, Angers, France.

Nicolas Clere (N)

UMR Inserm 1066, CNRS 6021, Université d'Angers, CHU, IBS, IRIS, MINT, UNIV Angers, INSERM, CNRS, Université Bretagne Loire, IBS-CHU, 4, rue Larrey, 49933, Angers, France. nicolas.clere@univ-angers.fr.

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Classifications MeSH