Effect of Tribulus terrestris saponins on proliferation of adipose-derived mesenchymal stem cells.
Adipose Tissue
/ cytology
Apoptosis
/ drug effects
Cell Proliferation
/ drug effects
Cell Survival
/ drug effects
Dose-Response Relationship, Drug
Humans
Hydrogen Peroxide
/ pharmacology
Mesenchymal Stem Cells
/ cytology
Oxidants
/ pharmacology
Phytotherapy
/ methods
Plant Extracts
/ pharmacology
Protective Agents
/ pharmacology
Saponins
/ pharmacology
Time Factors
Tribulus
/ chemistry
Tribulus terrestris saponins
adipose derived-mesenchymal stem cells
hydrogen peroxide
oxidative stress
Journal
Journal of cellular biochemistry
ISSN: 1097-4644
Titre abrégé: J Cell Biochem
Pays: United States
ID NLM: 8205768
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
received:
16
02
2018
accepted:
24
10
2018
pubmed:
15
12
2018
medline:
21
7
2020
entrez:
15
12
2018
Statut:
ppublish
Résumé
Adipose-derived mesenchymal stem cells (ASCs) transplantation has shown great promise for treating various diseases; however, poor viability of transplanted ASCs because of oxidative stress has limited its therapeutic efficiency. Plant saponins are recently been reported to have antioxidant activity tested in various cancer cell lines. This study was designed to investigate the protective effects of Tribulus terrestris saponins (TTS) on the proliferation of ASCs. The cytotoxic activity of hydrogen peroxide (H
Substances chimiques
Oxidants
0
Plant Extracts
0
Protective Agents
0
Saponins
0
Hydrogen Peroxide
BBX060AN9V
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
10082-10086Informations de copyright
© 2018 Wiley Periodicals, Inc.