Varicella zoster virus encephalitis in solid organ transplant recipients: Case series and review of literature.
encephalitis
herpes zoster
solid organ transplant
varicella zoster virus
Journal
Transplant infectious disease : an official journal of the Transplantation Society
ISSN: 1399-3062
Titre abrégé: Transpl Infect Dis
Pays: Denmark
ID NLM: 100883688
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
14
08
2018
revised:
12
10
2018
accepted:
21
11
2018
pubmed:
15
12
2018
medline:
3
5
2019
entrez:
15
12
2018
Statut:
ppublish
Résumé
Herpes zoster encephalitis (HZE) is a rare complication of varicella zoster virus (VZV) infection. We report two cases of HZE in solid organ transplant (SOT) recipients and review 10 other cases in the literature. In this review, rash was present in 67% of cases. Despite the absence of a rash, high clinical suspicion for HZE is necessary and empiric antiviral therapy should be considered. While with variable outcome, it was associated with high mortality rate of 42%. Prompt initiation of antiviral therapy remains crucial in decreasing morbidity and mortality from this fatal disease.
Substances chimiques
Antiviral Agents
0
Acyclovir
X4HES1O11F
Types de publication
Case Reports
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13038Informations de copyright
© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.