Colonic Ewing Sarcoma/PNET associated with liver metastases: A systematic review and case report.
Colon
Ewing Sarcoma
Extra osseous sarcoma
Liver metastases
PNET
Rectum
Journal
Pathology, research and practice
ISSN: 1618-0631
Titre abrégé: Pathol Res Pract
Pays: Germany
ID NLM: 7806109
Informations de publication
Date de publication:
Feb 2019
Feb 2019
Historique:
received:
07
10
2018
revised:
25
11
2018
accepted:
27
11
2018
pubmed:
17
12
2018
medline:
23
3
2019
entrez:
17
12
2018
Statut:
ppublish
Résumé
Ewing Sarcoma is a highly lethal undifferentiated tumor of bone. ES is a small round cell tumor with etiological and characteristic chromosomal translocations between TET/FET (TLS/FUS, EWSR1, and TAF15) and ETS (E26 transformation-specific) family genes. Generally, therapeutic approach for metastatic Ewing Sarcoma includes both local (surgery and radiotherapy) and systemic (chemotherapy) disease control with an overall cure rate of 20%. For extra-osseous tumors, the most common primary sites of disease are trunk, extremities, head and neck, retroperitoneum. Among other sites, Ewing Sarcoma/PNET may also rarely arise in colon and rectum. Even if colonic Ewing Sarcoma/PNET have been previously reported in 5 cases, none of those reports came from right side of the colon. In this article, we report the first case of right-sided Ewing Sarcoma with synchronous liver metastases completely responding to first line chemotherapy. Furthermore, we provide a systematic qualitative review of the current literature on adult colorectal Ewing Sarcoma using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).
Identifiants
pubmed: 30553605
pii: S0344-0338(18)31365-7
doi: 10.1016/j.prp.2018.11.021
pii:
doi:
Types de publication
Case Reports
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
387-391Informations de copyright
Copyright © 2018. Published by Elsevier GmbH.