Pharmacologically evoked apnoeas. Receptors and nervous pathways involved.
5-HT(1A) receptors
5-HT(3) receptors
Apnoea
TRPV1 receptors
Vagus nerve
μ receptors
Journal
Life sciences
ISSN: 1879-0631
Titre abrégé: Life Sci
Pays: Netherlands
ID NLM: 0375521
Informations de publication
Date de publication:
15 Jan 2019
15 Jan 2019
Historique:
received:
29
10
2018
revised:
05
12
2018
accepted:
12
12
2018
pubmed:
17
12
2018
medline:
12
1
2019
entrez:
17
12
2018
Statut:
ppublish
Résumé
This review analyses the knowledge about the incidence of transient apnoeic spells, induced by substances which activate vagal chemically sensitive afferents. It considers the specificity and expression of appropriate receptors, and relevant research on pontomedullary circuits contributing to a cessation of respiration. Insight is gained into an excitatory drive of 5-HT
Identifiants
pubmed: 30553870
pii: S0024-3205(18)30804-X
doi: 10.1016/j.lfs.2018.12.021
pii:
doi:
Substances chimiques
Receptors, Opioid, mu
0
Receptors, Serotonin, 5-HT3
0
TRPV Cation Channels
0
TRPV1 protein, human
0
Receptor, Serotonin, 5-HT1A
112692-38-3
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
237-242Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.