Status of antimicrobial stewardship programmes in Nigerian tertiary healthcare facilities: Findings and implications.
Anti-Bacterial Agents
/ administration & dosage
Antimicrobial Stewardship
/ standards
Cross-Sectional Studies
Drug Resistance, Multiple, Bacterial
Drug Utilization
/ statistics & numerical data
Geography
Humans
Nigeria
Practice Patterns, Physicians'
/ standards
Surveys and Questionnaires
Tertiary Care Centers
Antimicrobial resistance
Antimicrobial stewardship programme
Monitoring antibiotic use
Nigeria
Susceptibility testing
Tertiary hospitals
Journal
Journal of global antimicrobial resistance
ISSN: 2213-7173
Titre abrégé: J Glob Antimicrob Resist
Pays: Netherlands
ID NLM: 101622459
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
received:
30
04
2018
revised:
30
07
2018
accepted:
30
11
2018
pubmed:
18
12
2018
medline:
19
6
2020
entrez:
18
12
2018
Statut:
ppublish
Résumé
The problem of antimicrobial resistance (AMR) is increasing worldwide, with health-related and economic consequences. This is a concern in Africa, including Nigeria, the most populous country in Africa, with its high rates of infectious diseases. Approaches to reducing AMR include instigating antimicrobial stewardship programmes (ASPs) in hospitals. Currently, no information is available regarding the extent of ASPs in Nigerian hospitals. Consequently, the objective was to address this starting in tertiary hospitals. This was a cross-sectional, questionnaire-based study among tertiary healthcare facilities. Tertiary hospitals were chosen initially since if there are concerns in these training hospitals, such concerns will likely to be exacerbated in other hospitals. Completed questionnaires were received from 17 of 25 tertiary healthcare facilities across five of the six geopolitical regions of Nigeria. Ten (59%), four (24%), two (12%) and one (6%) respondents were in internal medicine, infectious diseases, medical microbiology and clinical pharmacology, respectively. Only six healthcare facilities (35%) had a formal organisational structure and a team responsible for ASP. Facility-specific treatment recommendations, based on local AMR patterns, were available in only four facilities (24%). Policies on approval for prescribing specified antimicrobials and formal procedures for reviewing their appropriateness after 48h were present in only two facilities (12%). A cumulative antimicrobial susceptibility report for the previous year was available in only two facilities (12%), and only one facility routinely monitored antimicrobial use. Significant inadequacies in the availability of ASPs were observed. This needs to be urgently addressed to reduce AMR rates in Nigeria.
Identifiants
pubmed: 30557686
pii: S2213-7165(18)30242-X
doi: 10.1016/j.jgar.2018.11.025
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
132-136Subventions
Organisme : Medical Research Council
ID : MC_PC_16090
Pays : United Kingdom
Informations de copyright
Copyright © 2018 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.